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An evaluation of the COVID-19 recommendation map identified diverging clinical and public health guidance
ZH. Nasir, D. Mertz, R. Nieuwlaat, N. Santesso, T. Lotfi, A. Motilall, L. Moja, L. Mbuagbaw, M. Klugar, AF. Turgeon, JL. Mathew, C. Canelo-Aybar, K. Pottie, O. Dewidar, MW. Langendam, A. Iorio, GE. Vist, JJ. Meerpohl, S. Flottorp, T. Kredo, T....
Language English Country United States
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
ProQuest Central
from 2003-01-01 to 2 months ago
Nursing & Allied Health Database (ProQuest)
from 2003-01-01 to 2 months ago
Health & Medicine (ProQuest)
from 2003-01-01 to 2 months ago
Health Management Database (ProQuest)
from 2003-01-01 to 2 months ago
Public Health Database (ProQuest)
from 2003-01-01 to 2 months ago
- MeSH
- COVID-19 * epidemiology MeSH
- Humans MeSH
- Public Health * MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
OBJECTIVES: To describe divergence between actionable statements issued by coronavirus disease 2019 (COVID-19) guideline developers cataloged on the "COVID-19 Recommendations and Gateway to Contextualization" platform. STUDY DESIGN AND SETTING: We defined divergence as at least two comparable actionable statements with different explicit judgments of strength, direction, or subgroup consideration of the population or intervention. We applied a content analysis to compare guideline development methods for a sample of diverging statements and to evaluate factors associated with divergence. RESULTS: Of the 138 guidelines evaluated, 85 (62%) contained at least one statement that diverged from another guideline. We identified 223 diverging statements in these 85 guidelines. We grouped statements into 66 clusters. Each cluster addressed the same population, intervention, and comparator group or just similar interventions. Clinical practice statements were more likely to diverge in an explicit judgment of strength or direction compared to public health statements. Statements were more likely to diverge in strength than direction. The date of publication, used evidence, interpretation of evidence, and contextualization considerations were associated with divergence. CONCLUSION: More than half of the assessed guidelines issued at least one diverging statement. This study helps in understanding the types of differences between guidelines issuing comparable statements and factors associated with their divergence.
American College of Physicians Philadelphia PA USA
Biostatistics Unit The Research Institute St Joseph's Healthcare Hamilton Ontario Canada
Bruyere Research Institute Ottawa Canada
CIBER de Epidemiología y Salud Pública Barcelona Spain
Cochrane Germany Cochrane Germany Foundation Freiburg Germany
Cochrane South Africa South African Medical Research Council Cape Town South Africa
Department of Biomedical Sciences for Health University of Milan Milan Italy
Department of Medicine McMaster University Hamilton Ontario Canada
Department of Medicine University of Ottawa Ottawa Ontario K1H 8M5 Canada
Dipartimento di Scienze Biomediche Humanitas University Milan Italy
Faculty of Dentistry Department of Oral Medicine and Periodontology Cairo University Cairo Egypt
Faculty of Health Sciences Queen's University 18 Barrie Street Kingston Ontario K7L 3N6 Canada
Michael G DeGroote Cochrane Canada and GRADE Centre McMaster University Hamilton Ontario Canada
Norwegian Institute of Public Health P O Box 222 Skøyen 0213 Oslo Norway
Postgraduate Institute of Medical Education and Research Chandigarh India
School of Epidemiology and Public Health University of Ottawa Canada
References provided by Crossref.org
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- $a Nasir, Zil H $u Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada
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- $a An evaluation of the COVID-19 recommendation map identified diverging clinical and public health guidance / $c ZH. Nasir, D. Mertz, R. Nieuwlaat, N. Santesso, T. Lotfi, A. Motilall, L. Moja, L. Mbuagbaw, M. Klugar, AF. Turgeon, JL. Mathew, C. Canelo-Aybar, K. Pottie, O. Dewidar, MW. Langendam, A. Iorio, GE. Vist, JJ. Meerpohl, S. Flottorp, T. Kredo, T. Piggott, M. Mathews, A. Qaseem, DK. Chu, P. Tugwell, J. Klugarová, H. Nelson, H. Hussein, J. Suvada, I. Neumann, HJ. Schünemann, eCOVID-19 recommendations map Collaborators
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- $a OBJECTIVES: To describe divergence between actionable statements issued by coronavirus disease 2019 (COVID-19) guideline developers cataloged on the "COVID-19 Recommendations and Gateway to Contextualization" platform. STUDY DESIGN AND SETTING: We defined divergence as at least two comparable actionable statements with different explicit judgments of strength, direction, or subgroup consideration of the population or intervention. We applied a content analysis to compare guideline development methods for a sample of diverging statements and to evaluate factors associated with divergence. RESULTS: Of the 138 guidelines evaluated, 85 (62%) contained at least one statement that diverged from another guideline. We identified 223 diverging statements in these 85 guidelines. We grouped statements into 66 clusters. Each cluster addressed the same population, intervention, and comparator group or just similar interventions. Clinical practice statements were more likely to diverge in an explicit judgment of strength or direction compared to public health statements. Statements were more likely to diverge in strength than direction. The date of publication, used evidence, interpretation of evidence, and contextualization considerations were associated with divergence. CONCLUSION: More than half of the assessed guidelines issued at least one diverging statement. This study helps in understanding the types of differences between guidelines issuing comparable statements and factors associated with their divergence.
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