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Prolonged survival in patients with local chronic infection after high-grade glioma treatment: Two case reports

P. Solár, Z. Mackerle, M. Hendrych, P. Pospisil, R. Lakomy, H. Valekova, M. Hermanova, R. Jancalek

. 2022 ; 12 (-) : 1073036. [pub] 20221216

Status neindexováno Jazyk angličtina Země Švýcarsko

Typ dokumentu kazuistiky

Perzistentní odkaz   https://www.medvik.cz/link/bmc23003349

High-grade gliomas are primary brain tumors with poor prognosis, despite surgical treatment followed by radiotherapy and concomitant chemotherapy. We present two cases of long-term survival in patients treated for high-grade glioma and concomitant prolonged bacterial wound infection. The first patient treated for glioblastoma IDH-wildtype had been without disease progression for 61 months from the first resected recurrence. Despite incomplete chemotherapy-induced myelosuppression in the second patient with anaplastic astrocytoma IDH-mutant, she died without disease relapse after 14 years from the diagnosis due to other comorbidities. We assume that the documented prolonged survival could be related to the bacterial infection.

Citace poskytuje Crossref.org

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