Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Baseline left atrial low-voltage area predicts recurrence after pulmonary vein isolation: WAVE-MAP AF results

Z. Starek, A. Di Cori, TR. Betts, G. Clerici, D. Gras, E. Lyan, P. Della Bella, J. Li, B. Hack, L. Zitella Verbick, P. Sommer

. 2023 ; 25 (9) : . [pub] 2023Aug02

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc23016624

Grantová podpora
Abbott

AIMS: Electro-anatomical mapping may be critical to identify atrial fibrillation (AF) subjects who require substrate modification beyond pulmonary vein isolation (PVI). The objective was to determine correlations between pre-ablation mapping characteristics and 12-month outcomes after a single PVI-only catheter ablation of AF. METHODS AND RESULTS: This study enrolled paroxysmal AF (PAF), early persistent AF (PsAF; 7 days-3 months), and non-early PsAF (>3-12 months) subjects undergoing de novo PVI-only radiofrequency catheter ablation. Sinus rhythm (SR) and AF voltage maps were created with the Advisor HD GridTM Mapping Catheter, Sensor EnabledTM for each subject, and the presence of low-voltage area (LVA) (low-voltage cutoffs: 0.1-1.5 mV) was investigated. Follow-up visits were at 3, 6, and 12 months, with a 24-h Holter monitor at 12 months. A Cox proportional hazards model identified associations between mapping data and 12-month recurrence after a single PVI procedure. The study enrolled 300 subjects (113 PAF, 86 early PsAF, and 101 non-early PsAF) at 18 centres. At 12 months, 75.5% of subjects were free from AF/atrial flutter (AFL)/atrial tachycardia (AT) recurrence. Univariate analysis found that arrhythmia recurrence did not correlate with AF diagnosis, but LVA was significantly correlated. Low-voltage area (<0.5 mV) >28% of the left atrium in SR [hazard ratio (HR): 4.82, 95% confidence interval (CI): 2.08-11.18; P = 0.0003] and >72% in AF (HR: 5.66, 95% CI: 2.34-13.69; P = 0.0001) was associated with a higher risk of AF/AFL/AT recurrence at 12 months. CONCLUSION: Larger extension of LVA was associated with an increased risk of arrhythmia recurrence. These subjects may benefit from substrate modification beyond PVI.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc23016624
003      
CZ-PrNML
005      
20231026105653.0
007      
ta
008      
231013s2023 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1093/europace/euad194 $2 doi
035    __
$a (PubMed)37470443
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Starek, Zdenek $u International Clinical Research Center, St. Anne's University Hospital Brno, Pekarska 664/53, Brno 60200, Czech Republic $u First Department of Internal Medicine/Cardioangiology, St. Anne's Hospital, Masaryk University, Pekarska 664/53, Brno 60200, Czech Republic $1 https://orcid.org/0000000295101386
245    10
$a Baseline left atrial low-voltage area predicts recurrence after pulmonary vein isolation: WAVE-MAP AF results / $c Z. Starek, A. Di Cori, TR. Betts, G. Clerici, D. Gras, E. Lyan, P. Della Bella, J. Li, B. Hack, L. Zitella Verbick, P. Sommer
520    9_
$a AIMS: Electro-anatomical mapping may be critical to identify atrial fibrillation (AF) subjects who require substrate modification beyond pulmonary vein isolation (PVI). The objective was to determine correlations between pre-ablation mapping characteristics and 12-month outcomes after a single PVI-only catheter ablation of AF. METHODS AND RESULTS: This study enrolled paroxysmal AF (PAF), early persistent AF (PsAF; 7 days-3 months), and non-early PsAF (>3-12 months) subjects undergoing de novo PVI-only radiofrequency catheter ablation. Sinus rhythm (SR) and AF voltage maps were created with the Advisor HD GridTM Mapping Catheter, Sensor EnabledTM for each subject, and the presence of low-voltage area (LVA) (low-voltage cutoffs: 0.1-1.5 mV) was investigated. Follow-up visits were at 3, 6, and 12 months, with a 24-h Holter monitor at 12 months. A Cox proportional hazards model identified associations between mapping data and 12-month recurrence after a single PVI procedure. The study enrolled 300 subjects (113 PAF, 86 early PsAF, and 101 non-early PsAF) at 18 centres. At 12 months, 75.5% of subjects were free from AF/atrial flutter (AFL)/atrial tachycardia (AT) recurrence. Univariate analysis found that arrhythmia recurrence did not correlate with AF diagnosis, but LVA was significantly correlated. Low-voltage area (<0.5 mV) >28% of the left atrium in SR [hazard ratio (HR): 4.82, 95% confidence interval (CI): 2.08-11.18; P = 0.0003] and >72% in AF (HR: 5.66, 95% CI: 2.34-13.69; P = 0.0001) was associated with a higher risk of AF/AFL/AT recurrence at 12 months. CONCLUSION: Larger extension of LVA was associated with an increased risk of arrhythmia recurrence. These subjects may benefit from substrate modification beyond PVI.
650    _2
$a lidé $7 D006801
650    12
$a fibrilace síní $x diagnóza $x chirurgie $7 D001281
650    12
$a venae pulmonales $x chirurgie $7 D011667
650    _2
$a srdeční frekvence $7 D006339
650    _2
$a výsledek terapie $7 D016896
650    _2
$a elektrofyziologické techniky kardiologické $7 D022062
650    _2
$a recidiva $7 D012008
650    _2
$a časové faktory $7 D013997
650    _2
$a srdeční síně $7 D006325
650    12
$a flutter síní $x diagnóza $x chirurgie $x etiologie $7 D001282
650    12
$a katetrizační ablace $x škodlivé účinky $x metody $7 D017115
655    _2
$a časopisecké články $7 D016428
700    1_
$a Di Cori, Andrea $u Second Division of Cardiovascular Diseases, Cardiac-Thoracic and Vascular Department, New Santa Chiara Hospital, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy $1 https://orcid.org/0000000230837376
700    1_
$a Betts, Timothy R $u Department of Cardiology, John Radcliffe Hospital, Oxford, UK $1 https://orcid.org/0000000190639905
700    1_
$a Clerici, Gael $u Cardiology Department, Rhythmology Unit, Centre Hospitalier Universitaire de La Reunion, La Reunion, France $1 https://orcid.org/0000000246316196
700    1_
$a Gras, Daniel $u Department of Cardiology, Hopital Prive du Confluent, Nantes, France $1 https://orcid.org/0000000279806036
700    1_
$a Lyan, Evgeny $u Department of Cardiology, Section of Electrophysiology, Herz-und Gefäßzentrum Bad Bevensen, Bad Bevensen, Germany $1 https://orcid.org/0000000196969227
700    1_
$a Della Bella, Paolo $u Arrhythmia Unit and Electrophysiology Laboratories, Ospedale San Raffaele, Milano, Italy $1 https://orcid.org/0000000183461387
700    1_
$a Li, Jingyun $u Abbott, Saint Paul, MN, USA
700    1_
$a Hack, Benjamin $u Abbott, Saint Paul, MN, USA
700    1_
$a Zitella Verbick, Laura $u Abbott, Saint Paul, MN, USA $1 https://orcid.org/0000000313599916
700    1_
$a Sommer, Philipp $u Department for Electrophysiology, Herz-und Diabetes Zentrum NRW, Bad Oeynhausen, Germany $1 https://orcid.org/0000000230378704
773    0_
$w MED00149837 $t Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology $x 1532-2092 $g Roč. 25, č. 9 (2023)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/37470443 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20231013 $b ABA008
991    __
$a 20231026105648 $b ABA008
999    __
$a ok $b bmc $g 2000254 $s 1202986
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2023 $b 25 $c 9 $e 2023Aug02 $i 1532-2092 $m Europace $n Europace $x MED00149837
GRA    __
$p Abbott
LZP    __
$a Pubmed-20231013

Najít záznam

Citační ukazatele

Možnosti archivace