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Severe Acute Kidney Injury in Children as a Rare Complication of Paroxysmal Cold Hemoglobinuria
J. Zieg, E. Flachsová, E. Linhartová, P. Konopásek, Š. Štolbová, N. Šimánková, F. Fencl, P. Pavlíček, M. Suková
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články
- MeSH
- akutní poškození ledvin * komplikace MeSH
- dítě MeSH
- erytrocyty MeSH
- hemolýza MeSH
- lidé MeSH
- nízká teplota MeSH
- paroxysmální hemoglobinurie * komplikace diagnóza MeSH
- retrospektivní studie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
Paroxysmal cold hemoglobinuria (PCH) is a rare condition in childhood characterized by complement-mediated premature destruction of red blood cells. PCH is associated with intravascular hemolysis causing hemoglobinuria, which may result in acute kidney injury of various severity. We aimed to retrospectively analyze clinical and laboratory features of children with PCH-associated acute kidney injury received at tertiary Pediatric Hematology and Nephrology Center, University Motol Hospital, Prague, Czech Republic during the period 2016 to 2022. We present here 3 children with PCH-associated acute kidney failure requiring renal replacement therapy. We highlight the association of PCH with kidney disease. Renal parameters and urine examination should be regularly tested in all children with PCH.
Anesthesiology and Intensive Care Medicine
Department of blood bank Motol University Hospital Prague Czech Republic
Citace poskytuje Crossref.org
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