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Worldwide survey on implantation of and outcomes for conduction system pacing with His bundle and left bundle branch area pacing leads
AC. Perino, PJ. Wang, M. Lloyd, F. Zanon, K. Fujiu, F. Osman, S. Briongos-Figuero, T. Sato, T. Aksu, M. Jastrzebski, S. Sideris, P. Rao, K. Boczar, X. Yuan-Ning, M. Wu, N. Namboodiri, R. Garcia, V. Kataria, J. De Pooter, O. Przibille, AK. Gehi,...
Language English Country Netherlands
Document type Journal Article
Grant support
UL1 TR003142
NCATS NIH HHS - United States
NLK
ProQuest Central
from 1997-07-01 to 1 year ago
Medline Complete (EBSCOhost)
from 2011-01-01 to 1 year ago
Health & Medicine (ProQuest)
from 1997-07-01 to 1 year ago
- MeSH
- Bradycardia * therapy MeSH
- Electrocardiography MeSH
- Bundle of His * MeSH
- Cardiac Pacing, Artificial MeSH
- Humans MeSH
- Cardiac Conduction System Disease MeSH
- Heart Conduction System MeSH
- Cross-Sectional Studies MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
BACKGROUND: Adoption and outcomes for conduction system pacing (CSP), which includes His bundle pacing (HBP) or left bundle branch area pacing (LBBAP), in real-world settings are incompletely understood. We sought to describe real-world adoption of CSP lead implantation and subsequent outcomes. METHODS: We performed an online cross-sectional survey on the implantation and outcomes associated with CSP, between November 15, 2020, and February 15, 2021. We described survey responses and reported HBP and LBBAP outcomes for bradycardia pacing and cardiac resynchronization CRT indications, separately. RESULTS: The analysis cohort included 140 institutions, located on 5 continents, who contributed data to the worldwide survey on CSP. Of these, 127 institutions (90.7%) reported experience implanting CSP leads. CSP and overall device implantation volumes were reported by 84 institutions. In 2019, the median proportion of device implants with CSP, HBP, and/or LBBAP leads attempted were 4.4% (interquartile range [IQR], 1.9-12.5%; range, 0.4-100%), 3.3% (IQR, 1.3-7.1%; range, 0.2-87.0%), and 2.5% (IQR, 0.5-24.0%; range, 0.1-55.6%), respectively. For bradycardia pacing indications, HBP leads, as compared to LBBAP leads, had higher reported implant threshold (median [IQR]: 1.5 V [1.3-2.0 V] vs 0.8 V [0.6-1.0 V], p = 0.0008) and lower ventricular sensing (median [IQR]: 4.0 mV [3.0-5.0 mV] vs. 10.0 mV [7.0-12.0 mV], p < 0.0001). CONCLUSION: In conclusion, CSP lead implantation has been broadly adopted but has yet to become the default approach at most surveyed institutions. As the indications and data for CSP continue to evolve, strategies to educate and promote CSP lead implantation at institutions without CSP lead implantation experience would be necessary.
1st Affiliated Hospital of Nanjing Medical University Jiangsu Provincial Hospital Nanjing China
Ankara City Hospital Ankara Turkey
ARNAS Civico Hospital Palermo Italy
Aston University Birmingham UK
Azienda Ospedaliera Universitaria Senese Siena Italy
Azienda Ospedaliero Universitaria Di Ferrara Cona Italy
Baylor University Medical Center Dallas USA
Beacon Hospital Dublin Ireland
Bern University Hospital Bern Switzerland
Caen University Hospital Caen France
Cardioangiologic Centre Bethanien Frankfurt Germany
Cardiocenter 3Rd Faculty of Medicine Charles University Prague Czechia
Centro de Investigaciones Biomédicas en RED en Enfermedades Cardiovasculares Madrid Spain
Children's National Hospital Washington D C USA
China Medical University Hospital Taichung Taiwan
Columbia University New York NY USA
Emory University School of Medicine Atlanta USA
Ente Ecclesiastico Ospedale Miulli Acquaviva Delle Fonti BA Italy
Fujita Health University Toyoake Japan
Geisinger Heart Institute Danville USA
Hippokration General Hospital Athens Greece
Holy Family Hospital New Delhi India
Hospital Alvaro Cunqueiro Vigo Spain
Hospital Clínic de Barcelona Universitat de Barcelona Barcelona Spain
Hospital General Universitario Gregorio Marañon Madrid Spain
Hospital HM Monteprincipe Madrid Spain
Hospital of the University of Pennsylvania Philadelphia USA
Hospital Salud Integral Managua Nicaragua
Hospital Universitari 1 Politècnic La Fe Valencia Spain
Hospital Universitario Infanta Leonor Madrid Spain
Hospital Universitario Virgen del Rocío Seville Spain
IRCCS San Raffaele Hospital Segrate Italy
Kaohsiung Chang Gung Memorial Hospital Kaohsiung Taiwan
Kobari General Hospital Noda Japan
Krannert Institute of Cardiology Indiana University Avon IN USA
Krishna Institute of Medical Sciences Karad India
Kumamoto University Hospital Kumamoto Japan
Kyorin University School of Medicine Mitaka Japan
Kyoto Katsura Hospital Kyoto Japan
Lewis Katz School of Medicine at Temple University Philadelphia USA
Lifespan Cardiovascular Institute Brown University Providence USA
Marche Polytechnic University Ancona Italy
Medical College University of Rzeszów Rzeszów Poland
Monash Health Melbourne Australia
Nagoya University Graduate School of Medicine Nagoya Japan
National Cerebral and Cardiovascular Center Suita Japan
National Medical Research Center VA Almazov Saint Petersburg Russia
New York Presbyterian Brooklyn Methodist Hospital New York NY USA
Ochsner Medical Center New Orleans USA
Onassis Cardiac Surgery Center Kallithea Greece
Ospedale Luigi Sacco Milan Italy
Poznań University of Medical Sciences Poznań Poland
Princess of Wales Hospital Bridgend UK
Queen Elizabeth Hospital Birmingham UK
Royal Brompton Hospital London UK
Royal Papworth Hospital NHS Trust Cambridge UK
Rush University Medical Center Chicago USA
San Raffaele Scientific Institute Segrate Italy
Santa Maria Della Misericordia General Hospital Perugia Italy
School of Mdeicine Jagiellonian University Krakow Poland
School of Medicine and Public Health University of Wisconsin Madison USA
School of Medicine China Medical University Taichung Taiwan
Shanghai General Hospital Shanghai China
SOS Cardio Cardiology Hospital Center Florianópolis Brazil
Southlake Regional Health Centre Newmarket Canada
Sree Chitra Institute for Medical Sciences and Technology Thiruvananthapuram India
St Joseph's Heart Rhythm Center Rzeszów Poland
Steward St Elizabeth's Medical Center Boston USA
The John Paul 2 Hospital Krakow Poland
The University of Tokyo Tokyo Japan
UMass Memorial Health Cancer Center Worcester USA
Universitätsklinikum Ulm Ulm Germany
University Hospital Coventry Conventry UK
University Hospital Freiburg Freiburg Germany
University Hospital Germans Trias 1 Pujol Barcelona Spain
University Hospital Ghent Ghent Belgium
University Hospital Heidelberg Heidelberg Germany
University Hospital October 12 Madrid Spain
University Hospital of Poitiers Poitiers France
University Hospital of Rennes Rennes France
University of Arizona College of Medicine Tucson USA
University of Arkansas Medical Sciences Little Rock USA
University of Calgary Calgary Canada
University of California San Diego Health System San Diego USA
University of Nebraska Medical Center Omaha USA
University of North Carolina School of Medicine Chapel Hill USA
University of Pittsburgh Pittsburgh USA
University of Siena Siena Italy
University of Tours Tours France
University of Utah School of Medicine Salt Lake City USA
West China Hospital Sichuan University Chengdu China
References provided by Crossref.org
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- $a Perino, Alexander C $u Center for Academic Medicine, Department of Medicine/Division of Cardiovascular Medicine, Stanford University School of Medicine, 453 Quarry Road, Palo Alto, CA, 94304, USA. aperino@stanford.edu $1 https://orcid.org/0000000154828055
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- $a Worldwide survey on implantation of and outcomes for conduction system pacing with His bundle and left bundle branch area pacing leads / $c AC. Perino, PJ. Wang, M. Lloyd, F. Zanon, K. Fujiu, F. Osman, S. Briongos-Figuero, T. Sato, T. Aksu, M. Jastrzebski, S. Sideris, P. Rao, K. Boczar, X. Yuan-Ning, M. Wu, N. Namboodiri, R. Garcia, V. Kataria, J. De Pooter, O. Przibille, AK. Gehi, O. Cano, G. Katsouras, B. Cai, K. Astheimer, T. Tanawuttiwat, T. Datino, J. Rizkallah, M. Alasti, G. Feld, MT. Barrio-Lopez, M. Gilmore, S. Conti, S. Yanagisawa, JH. Indik, J. Zou, SA. Saha, D. Rodriguez-Munoz, KC. Chang, DS. Lebedev, MA. Leal, A. Haeberlin, ARJD. Forno, M. Orlov, M. Frutos, P. Cabanas-Grandio, J. Lyne, F. Leyva, JM. Tolosana, P. Ollitrault, P. Vergara, C. Balla, SR. Devabhaktuni, G. Forleo, KP. Letsas, A. Verma, JP. Moak, AB. Shelke, K. Curila, EM. Cronin, P. Futyma, EY. Wan, PE. Lazzerini, F. Bisbal, M. Casella, G. Turitto, L. Rosenthal, TJ. Bunch, A. Baszko, N. Clementy, YM. Cha, HC. Chen, V. Galand, R. Schaller, JWE. Jarman, M. Harada, Y. Wei, K. Kusano, C. Schmidt, MAA. Hurtado, N. Naksuk, T. Hoshiyama, K. Kancharla, Y. Iida, M. Mizobuchi, DP. Morin, S. Cay, G. Paglino, T. Dahme, S. Agarwal, P. Vijayaraman, PS. Sharma
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- $a BACKGROUND: Adoption and outcomes for conduction system pacing (CSP), which includes His bundle pacing (HBP) or left bundle branch area pacing (LBBAP), in real-world settings are incompletely understood. We sought to describe real-world adoption of CSP lead implantation and subsequent outcomes. METHODS: We performed an online cross-sectional survey on the implantation and outcomes associated with CSP, between November 15, 2020, and February 15, 2021. We described survey responses and reported HBP and LBBAP outcomes for bradycardia pacing and cardiac resynchronization CRT indications, separately. RESULTS: The analysis cohort included 140 institutions, located on 5 continents, who contributed data to the worldwide survey on CSP. Of these, 127 institutions (90.7%) reported experience implanting CSP leads. CSP and overall device implantation volumes were reported by 84 institutions. In 2019, the median proportion of device implants with CSP, HBP, and/or LBBAP leads attempted were 4.4% (interquartile range [IQR], 1.9-12.5%; range, 0.4-100%), 3.3% (IQR, 1.3-7.1%; range, 0.2-87.0%), and 2.5% (IQR, 0.5-24.0%; range, 0.1-55.6%), respectively. For bradycardia pacing indications, HBP leads, as compared to LBBAP leads, had higher reported implant threshold (median [IQR]: 1.5 V [1.3-2.0 V] vs 0.8 V [0.6-1.0 V], p = 0.0008) and lower ventricular sensing (median [IQR]: 4.0 mV [3.0-5.0 mV] vs. 10.0 mV [7.0-12.0 mV], p < 0.0001). CONCLUSION: In conclusion, CSP lead implantation has been broadly adopted but has yet to become the default approach at most surveyed institutions. As the indications and data for CSP continue to evolve, strategies to educate and promote CSP lead implantation at institutions without CSP lead implantation experience would be necessary.
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