• Je něco špatně v tomto záznamu ?

Prognostic value of the 5-SENSE Score to predict focality of the seizure-onset zone as assessed by stereoelectroencephalography: a prospective international multicentre validation study

A. Astner-Rohracher, A. Ho, J. Archer, F. Bartolomei, M. Brazdil, M. Cacic Hribljan, J. Castellano, I. Dolezalova, ME. Fabricius, M. Garcés-Sanchez, K. Hammam, A. Ikeda, K. Ikeda, P. Kahane, G. Kalamangalam, G. Kalss, M. Khweileh, K. Kobayashi,...

. 2024 ; 6 (2) : e000765. [pub] 20240821

Status neindexováno Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc24017991

INTRODUCTION: Epilepsy surgery is the only curative treatment for patients with drug-resistant focal epilepsy. Stereoelectroencephalography (SEEG) is the gold standard to delineate the seizure-onset zone (SOZ). However, up to 40% of patients are subsequently not operated as no focal non-eloquent SOZ can be identified. The 5-SENSE Score is a 5-point score to predict whether a focal SOZ is likely to be identified by SEEG. This study aims to validate the 5-SENSE Score, improve score performance by incorporating auxiliary diagnostic methods and evaluate its concordance with expert decisions. METHODS AND ANALYSIS: Non-interventional, observational, multicentre, prospective study including 200 patients with drug-resistant epilepsy aged ≥15 years undergoing SEEG for identification of a focal SOZ and 200 controls at 22 epilepsy surgery centres worldwide. The primary objective is to assess the diagnostic accuracy and generalisability of the 5-SENSE in predicting focality in SEEG in a prospective cohort. Secondary objectives are to optimise score performance by incorporating auxiliary diagnostic methods and to analyse concordance of the 5-SENSE Score with the expert decisions made in the multidisciplinary team discussion. ETHICS AND DISSEMINATION: Prospective multicentre validation of the 5-SENSE score may lead to its implementation into clinical practice to assist clinicians in the difficult decision of whether to proceed with implantation. This study will be conducted in accordance with the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (2014). We plan to publish the study results in a peer-reviewed full-length original article and present its findings at scientific conferences. TRIAL REGISTRATION NUMBER: NCT06138808.

Biostatistics and Big Medical Data Paracelsus Medical Private University Salzburg Austria

Bladin Berkovic Comprehensive Epilepsy Program The University of Melbourne Medicine at Austin Health Heidelberg Victoria Australia

Clinical Medicine University of Copenhagen Faculty of Health and Medical Sciences Kobenhavn Denmark

Clinical Neurophysiology Aarhus University Hospital Aarhus Denmark

Clinical Neurophysiology Rigshospitalet Kobenhavn Denmark

Department of Neuroscience Central Clinical School Monash University Faculty of Medicine Nursing and Health Sciences Melbourne Victoria Australia

Epilepsy Centre University Hospital Freiburg Department of Neurology Freiburg im Breisgau Germany

Institute for Child and Adolescent with Epilepsy Centre Hospitalier Universitaire Vaudois Lausanne Switzerland

Monash University Clayton Victoria Australia

Neurology Aix Marseille Universite Marseille France

Neurology Alfred Hospital Melbourne Victoria Australia

Neurology Dalhousie University Faculty of Medicine Halifax Nova Scotia Canada

Neurology Duke University Durham North Carolina USA

Neurology Grenoble Alpes University Hospital Grenoble France

Neurology Hospital del Mar Barcelona Spain

Neurology Hospital Universitari i Politècnic La Fe Valencia Spain

Neurology Kyoto University Graduate School of Medicine Faculty of Medicine Kyoto Japan

Neurology Masaryk University Faculty of Medicine Brno Czech Republic

Neurology Medical University of Innsbruck Department of Neurology and Neurosurgery Innsbruck Austria

Neurology Montreal Neurological Institute Hospital Montreal Quebec Canada

Neurology Paracelsus Medical University Salzburg Salzburg Austria

Neurology University of Florida Gainesville Florida USA

Neurology University of Medicine and Pharmacy Carol Davila Bucharest Bucuresti Romania

Neurology University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA

Neurology University of Texas McGovern Medical School Houston Texas USA

Neurology Western University Schulich School of Medicine and Dentistry London Ontario Canada

Neurosciences Mater Hospital Brisbane Brisbane Queensland Australia

Northwestern University Feinberg School of Medicine Chicago Illinois USA

Service de Neurophysiologie Clinique INSERM U751 CHU Timone Marseille France

UQ Faculty of Medicine Herston Queensland Australia

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24017991
003      
CZ-PrNML
005      
20241016081810.0
007      
ta
008      
241008s2024 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1136/bmjno-2024-000765 $2 doi
035    __
$a (PubMed)39175939
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Astner-Rohracher, Alexandra $u Neurology, Medical University of Innsbruck Department of Neurology and Neurosurgery, Innsbruck, Austria $1 https://orcid.org/000000021132302X
245    10
$a Prognostic value of the 5-SENSE Score to predict focality of the seizure-onset zone as assessed by stereoelectroencephalography: a prospective international multicentre validation study / $c A. Astner-Rohracher, A. Ho, J. Archer, F. Bartolomei, M. Brazdil, M. Cacic Hribljan, J. Castellano, I. Dolezalova, ME. Fabricius, M. Garcés-Sanchez, K. Hammam, A. Ikeda, K. Ikeda, P. Kahane, G. Kalamangalam, G. Kalss, M. Khweileh, K. Kobayashi, P. Kwan, JA. Laing, M. Leitinger, S. Lhatoo, J. Makhalova, A. McGonigal, I. Mindruta, MM. Mizera, A. Neal, I. Oane, P. Parikh, P. Perucca, F. Pizzo, R. Rocamora, P. Ryvlin, V. San Antonio Arce, S. Schuele, A. Schulze-Bonhage, A. Suller Marti, A. Urban, V. Villanueva, L. Vilella Bertran, B. Whatley, S. Beniczky, E. Trinka, G. Zimmermann, B. Frauscher
520    9_
$a INTRODUCTION: Epilepsy surgery is the only curative treatment for patients with drug-resistant focal epilepsy. Stereoelectroencephalography (SEEG) is the gold standard to delineate the seizure-onset zone (SOZ). However, up to 40% of patients are subsequently not operated as no focal non-eloquent SOZ can be identified. The 5-SENSE Score is a 5-point score to predict whether a focal SOZ is likely to be identified by SEEG. This study aims to validate the 5-SENSE Score, improve score performance by incorporating auxiliary diagnostic methods and evaluate its concordance with expert decisions. METHODS AND ANALYSIS: Non-interventional, observational, multicentre, prospective study including 200 patients with drug-resistant epilepsy aged ≥15 years undergoing SEEG for identification of a focal SOZ and 200 controls at 22 epilepsy surgery centres worldwide. The primary objective is to assess the diagnostic accuracy and generalisability of the 5-SENSE in predicting focality in SEEG in a prospective cohort. Secondary objectives are to optimise score performance by incorporating auxiliary diagnostic methods and to analyse concordance of the 5-SENSE Score with the expert decisions made in the multidisciplinary team discussion. ETHICS AND DISSEMINATION: Prospective multicentre validation of the 5-SENSE score may lead to its implementation into clinical practice to assist clinicians in the difficult decision of whether to proceed with implantation. This study will be conducted in accordance with the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (2014). We plan to publish the study results in a peer-reviewed full-length original article and present its findings at scientific conferences. TRIAL REGISTRATION NUMBER: NCT06138808.
590    __
$a NEINDEXOVÁNO
655    _2
$a časopisecké články $7 D016428
700    1_
$a Ho, Alyssa $u Neurology, Duke University, Durham, North Carolina, USA
700    1_
$a Archer, John $u Bladin-Berkovic Comprehensive Epilepsy Program, The University of Melbourne Medicine at Austin Health, Heidelberg, Victoria, Australia
700    1_
$a Bartolomei, Fabrice $u Service de Neurophysiologie Clinique, INSERM U751, CHU Timone, Marseille, France $u Neurology, Aix-Marseille Universite, Marseille, France $1 https://orcid.org/0000000216780297
700    1_
$a Brazdil, Milan $u Neurology, Masaryk University Faculty of Medicine, Brno, Czech Republic
700    1_
$a Cacic Hribljan, Melita $u Clinical Neurophysiology, Rigshospitalet, Kobenhavn, Denmark
700    1_
$a Castellano, James $u Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
700    1_
$a Dolezalova, Irena $u Neurology, Masaryk University Faculty of Medicine, Brno, Czech Republic
700    1_
$a Fabricius, Martin Ejler $u Clinical Neurophysiology, Rigshospitalet, Kobenhavn, Denmark $u Clinical Medicine, University of Copenhagen Faculty of Health and Medical Sciences, Kobenhavn, Denmark
700    1_
$a Garcés-Sanchez, Mercedes $u Neurology, Hospital Universitari i Politècnic La Fe, Valencia, Spain
700    1_
$a Hammam, Kahina $u Neurology, Aix-Marseille Universite, Marseille, France
700    1_
$a Ikeda, Akio $u Neurology, Kyoto University Graduate School of Medicine Faculty of Medicine, Kyoto, Japan
700    1_
$a Ikeda, Kristin $u Neurology, Dalhousie University Faculty of Medicine, Halifax, Nova Scotia, Canada
700    1_
$a Kahane, Philippe $u Neurology, Grenoble Alpes University Hospital, Grenoble, France
700    1_
$a Kalamangalam, Giridhar $u Neurology, University of Florida, Gainesville, Florida, USA
700    1_
$a Kalss, Gudrun $u Neurology, Paracelsus Medical University Salzburg, Salzburg, Austria
700    1_
$a Khweileh, Mays $u Neurology, Duke University, Durham, North Carolina, USA
700    1_
$a Kobayashi, Katsuya $u Neurology, Kyoto University Graduate School of Medicine Faculty of Medicine, Kyoto, Japan
700    1_
$a Kwan, Patrick $u Department of Neuroscience, Central Clinical School, Monash University Faculty of Medicine Nursing and Health Sciences, Melbourne, Victoria, Australia
700    1_
$a Laing, Joshua Andrew $u Neurology, Alfred Hospital, Melbourne, Victoria, Australia
700    1_
$a Leitinger, Markus $u Neurology, Paracelsus Medical University Salzburg, Salzburg, Austria
700    1_
$a Lhatoo, Samden $u Neurology, University of Texas McGovern Medical School, Houston, Texas, USA
700    1_
$a Makhalova, Julia $u Neurology, Aix-Marseille Universite, Marseille, France
700    1_
$a McGonigal, Aileen $u Neurosciences, Mater Hospital Brisbane, Brisbane, Queensland, Australia $u UQ Faculty of Medicine, Herston, Queensland, Australia $1 https://orcid.org/0000000167755318
700    1_
$a Mindruta, Iona $u Neurology, University of Medicine and Pharmacy Carol Davila Bucharest, Bucuresti, Romania
700    1_
$a Mizera, Mary Margaret $u Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
700    1_
$a Neal, Andrew $u Neurology, Alfred Hospital, Melbourne, Victoria, Australia
700    1_
$a Oane, Irina $u Neurology, University of Medicine and Pharmacy Carol Davila Bucharest, Bucuresti, Romania
700    1_
$a Parikh, Prachi $u Neurology, Duke University, Durham, North Carolina, USA
700    1_
$a Perucca, Piero $u Monash University, Clayton, Victoria, Australia
700    1_
$a Pizzo, Francesca $u Neurology, Aix-Marseille Universite, Marseille, France
700    1_
$a Rocamora, Rodrigo $u Neurology, Hospital del Mar, Barcelona, Spain
700    1_
$a Ryvlin, Philippe $u Institute for Child and Adolescent with Epilepsy (IDEE), Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
700    1_
$a San Antonio Arce, Victoria $u Epilepsy Centre, University Hospital Freiburg Department of Neurology, Freiburg im Breisgau, Germany
700    1_
$a Schuele, Stephan $u Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
700    1_
$a Schulze-Bonhage, Andreas $u Epilepsy Centre, University Hospital Freiburg Department of Neurology, Freiburg im Breisgau, Germany
700    1_
$a Suller Marti, Ana $u Neurology, Western University Schulich School of Medicine & Dentistry, London, Ontario, Canada
700    1_
$a Urban, Alexandra $u Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
700    1_
$a Villanueva, Vincente $u Neurology, Hospital Universitari i Politècnic La Fe, Valencia, Spain
700    1_
$a Vilella Bertran, Laura $u Neurology, Hospital del Mar, Barcelona, Spain
700    1_
$a Whatley, Benjamin $u Neurology, Dalhousie University Faculty of Medicine, Halifax, Nova Scotia, Canada
700    1_
$a Beniczky, Sandor $u Clinical Neurophysiology, Aarhus University Hospital, Aarhus, Denmark
700    1_
$a Trinka, Eugen $u Neurology, Paracelsus Medical University Salzburg, Salzburg, Austria
700    1_
$a Zimmermann, Georg $u Biostatistics and Big Medical Data, Paracelsus Medical Private University, Salzburg, Austria
700    1_
$a Frauscher, Birgit $u Neurology, Duke University, Durham, North Carolina, USA $u Neurology, Montreal Neurological Institute-Hospital, Montreal, Quebec, Canada
773    0_
$w MED00215629 $t BMJ neurology open $x 2632-6140 $g Roč. 6, č. 2 (2024), s. e000765
856    41
$u https://pubmed.ncbi.nlm.nih.gov/39175939 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20241008 $b ABA008
991    __
$a 20241016081805 $b ABA008
999    __
$a ok $b bmc $g 2196432 $s 1229942
BAS    __
$a 3
BAS    __
$a PreBMC-PubMed-not-MEDLINE
BMC    __
$a 2024 $b 6 $c 2 $d e000765 $e 20240821 $i 2632-6140 $m BMJ neurology open $n BMJ Neurol Open $x MED00215629
LZP    __
$a Pubmed-20241008

Najít záznam

Citační ukazatele

    Možnosti archivace