-
Je něco špatně v tomto záznamu ?
Czech Honeydew Honeys-A Potential Source of Local Medical Honey with Strong Antimicrobial Activity
L. Pudelka, R. Sleha, S. Janovska, V. Radochova, P. Bostik
Status neindexováno Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články
Grantová podpora
SV/FVZ202009
The Specific University Research provided by Ministry of Education Youth and Sports
DZRO-FVZ22-ZHN II
The Ministry of Defence of the Czech Republic
NLK
Directory of Open Access Journals
od 2009
Free Medical Journals
od 2009
PubMed Central
od 2004
Europe PubMed Central
od 2004
ProQuest Central
od 2004-01-01
Open Access Digital Library
od 2004-01-01
Open Access Digital Library
od 2009-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2004
PubMed
39065691
DOI
10.3390/ph17070840
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
An increasing resistance of microbes to antibiotics, the emergence of multidrug-resistant and extremely resistant strains, and the long time needed to develop new antibiotics are driving the search for additional sources of antibacterial agents. The aim of the study was to compare the efficacy of Czech honeys with already available pharmaceutical agents containing medicinal honey, and to perform basic biochemical analysis of Czech samples, including detection of undesirable chemical substances. The results showed strong antibacterial activity of Czech honeydew honeys compared to the control group, especially against G+ pathogens, with an average MIC of 9.44% compared to 17.54%, and comparable activity against G- of 16.48% versus 16.66%. In addition to the strong antibacterial activity, this study confirmed the safety and quality of Czech honeys and helped to select the character of a possible source for in vivo testing and subsequent clinical trials.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc24018328
- 003
- CZ-PrNML
- 005
- 20241016081918.0
- 007
- ta
- 008
- 241008s2024 sz f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3390/ph17070840 $2 doi
- 035 __
- $a (PubMed)39065691
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sz
- 100 1_
- $a Pudelka, Ludovit $u Department of Emergency Medicine and Military General Medicine, Military Faculty of Medicine, University of Defence, 500 01 Hradec Kralove, Czech Republic
- 245 10
- $a Czech Honeydew Honeys-A Potential Source of Local Medical Honey with Strong Antimicrobial Activity / $c L. Pudelka, R. Sleha, S. Janovska, V. Radochova, P. Bostik
- 520 9_
- $a An increasing resistance of microbes to antibiotics, the emergence of multidrug-resistant and extremely resistant strains, and the long time needed to develop new antibiotics are driving the search for additional sources of antibacterial agents. The aim of the study was to compare the efficacy of Czech honeys with already available pharmaceutical agents containing medicinal honey, and to perform basic biochemical analysis of Czech samples, including detection of undesirable chemical substances. The results showed strong antibacterial activity of Czech honeydew honeys compared to the control group, especially against G+ pathogens, with an average MIC of 9.44% compared to 17.54%, and comparable activity against G- of 16.48% versus 16.66%. In addition to the strong antibacterial activity, this study confirmed the safety and quality of Czech honeys and helped to select the character of a possible source for in vivo testing and subsequent clinical trials.
- 590 __
- $a NEINDEXOVÁNO
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Sleha, Radek $u Department of Epidemiology, Military Faculty of Medicine, University of Defence, 500 01 Hradec Kralove, Czech Republic $1 https://orcid.org/0000000173599147
- 700 1_
- $a Janovska, Sylva $u Department of Epidemiology, Military Faculty of Medicine, University of Defence, 500 01 Hradec Kralove, Czech Republic $1 https://orcid.org/0000000323848875 $7 xx0033210
- 700 1_
- $a Radochova, Vera $u Animal Laboratory, Military Faculty of Medicine, University of Defence, 500 01 Hradec Kralove, Czech Republic $1 https://orcid.org/0000000214775451
- 700 1_
- $a Bostik, Pavel $u Department of Epidemiology, Military Faculty of Medicine, University of Defence, 500 01 Hradec Kralove, Czech Republic $u Department of Medical Microbiology, University Hospital in Hradec Kralove, 500 01 Hradec Kralove, Czech Republic $1 https://orcid.org/0000000326916458
- 773 0_
- $w MED00184066 $t Pharmaceuticals $x 1424-8247 $g Roč. 17, č. 7 (2024)
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/39065691 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y - $z 0
- 990 __
- $a 20241008 $b ABA008
- 991 __
- $a 20241016081913 $b ABA008
- 999 __
- $a ok $b bmc $g 2196523 $s 1230281
- BAS __
- $a 3
- BAS __
- $a PreBMC-PubMed-not-MEDLINE
- BMC __
- $a 2024 $b 17 $c 7 $e 20240627 $i 1424-8247 $m Pharmaceuticals $n Pharmaceuticals (Basel) $x MED00184066
- GRA __
- $a SV/FVZ202009 $p The Specific University Research provided by Ministry of Education Youth and Sports
- GRA __
- $a DZRO-FVZ22-ZHN II $p The Ministry of Defence of the Czech Republic
- LZP __
- $a Pubmed-20241008
