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Nuts and bolts of the behavioural manipulation by Toxoplasma gondii
A. Vyas
Language English Country Czech Republic
Document type Journal Article, Review
NLK
Free Medical Journals
from 1966
ProQuest Central
from 2004-01-01 to 3 months ago
Health & Medicine (ProQuest)
from 2004-01-01 to 3 months ago
Public Health Database (ProQuest)
from 2004-01-01 to 3 months ago
ROAD: Directory of Open Access Scholarly Resources
from 1982
PubMed
39412143
DOI
10.14411/fp.2024.017
Knihovny.cz E-resources
- MeSH
- Behavior, Animal * physiology MeSH
- Host-Parasite Interactions * MeSH
- Rats MeSH
- Humans MeSH
- Toxoplasma * physiology MeSH
- Toxoplasmosis, Animal parasitology MeSH
- Toxoplasmosis parasitology MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
In this review, I take the first-person perspective of a neuroscientist interested in Toxoplasma gondii (Nicolle et Manceaux, 1908). I reflect on the value of behavioural manipulation as a perturbation tool to understand the organisation of behaviour within the brain. Toxoplasma gondii infection reduces the aversion of rats to the olfactory cues of cat presence. This change in behaviour is one of the often-discussed exemplars of host-parasite coevolution, culminating in the manipulation of the host behaviour for the benefit of the parasite. Such coevolution also means that we can use host-parasite systems as tools to derive fundamental insights about the host brain itself.
References provided by Crossref.org
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