Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Effects of three kinds of Chinese herbs on growth performance, oocysts output and gut microbiota in growing lambs with coccidiosis

Y. He, Z. Wang, S. Li, P. Chen, K. Liu, M. Li, Y. Wang, A. Shaukat, M. Abdullah, S. Li, S. Huang, F. Jian

. 2024 ; 71 (-) : . [pub] 20240417

Language English Country Czech Republic

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc25000313

Coccidiosis is a protozoan intestinal disease that reduces the production of the sheep industry and causes large economic losses for sheep. Although chemically synthesised drugs are routinely employed to treat coccidiosis in sheep, the anticoccidial drug resistance and drug residues in edible meat have prompted an urgent search for alternatives. Herein, the anticoccidial properties of diclazuril, a conventional anticoccidial drug, and Allium sativum, Houttuynia cordata and Portulaca oleracea were assessed. Forty 45-day-old lambs naturally infected with Eimeria spp. were selected and randomly divided into five groups. The results showed that the sheep treated for coccidiosis had considerably decreased average daily gain (ADG) during both administration and withdrawal of the drug compared to the control group. Furthermore, at days 14, 21, 28 and 35, respectively, the three herbs and diclazuril had similar anticoccidial effects, with lower oocysts per gram (OPG) than the control group. On day 78, OPG in the three herbal groups was significantly lower than in the diclazuril group. In addition, the abundance and composition of the gut microbiota were changed in sheep treated with the three herbs and diclazuril compared to the untreated sheep. Moreover, some intestinal microorganisms have a correlation with OPG and ADG when using Spearman correlation analysis. In summary, our results suggest that all three herbs produce anticoccidial effects similar to diclazuril and modulate the balance of gut microbiota in growing lambs.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc25000313
003      
CZ-PrNML
005      
20250110092633.0
007      
ta
008      
250107e20240417xr f 000 0|eng||
009      
AR
024    7_
$a 10.14411/fp.2024.009 $2 doi
035    __
$a (PubMed)38813809
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a He, Yanfeng $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
245    10
$a Effects of three kinds of Chinese herbs on growth performance, oocysts output and gut microbiota in growing lambs with coccidiosis / $c Y. He, Z. Wang, S. Li, P. Chen, K. Liu, M. Li, Y. Wang, A. Shaukat, M. Abdullah, S. Li, S. Huang, F. Jian
520    9_
$a Coccidiosis is a protozoan intestinal disease that reduces the production of the sheep industry and causes large economic losses for sheep. Although chemically synthesised drugs are routinely employed to treat coccidiosis in sheep, the anticoccidial drug resistance and drug residues in edible meat have prompted an urgent search for alternatives. Herein, the anticoccidial properties of diclazuril, a conventional anticoccidial drug, and Allium sativum, Houttuynia cordata and Portulaca oleracea were assessed. Forty 45-day-old lambs naturally infected with Eimeria spp. were selected and randomly divided into five groups. The results showed that the sheep treated for coccidiosis had considerably decreased average daily gain (ADG) during both administration and withdrawal of the drug compared to the control group. Furthermore, at days 14, 21, 28 and 35, respectively, the three herbs and diclazuril had similar anticoccidial effects, with lower oocysts per gram (OPG) than the control group. On day 78, OPG in the three herbal groups was significantly lower than in the diclazuril group. In addition, the abundance and composition of the gut microbiota were changed in sheep treated with the three herbs and diclazuril compared to the untreated sheep. Moreover, some intestinal microorganisms have a correlation with OPG and ADG when using Spearman correlation analysis. In summary, our results suggest that all three herbs produce anticoccidial effects similar to diclazuril and modulate the balance of gut microbiota in growing lambs.
650    _2
$a zvířata $7 D000818
650    12
$a kokcidióza $x veterinární $x farmakoterapie $x parazitologie $7 D003048
650    12
$a střevní mikroflóra $x účinky léků $7 D000069196
650    _2
$a ovce $7 D012756
650    12
$a nemoci ovcí $x parazitologie $x farmakoterapie $7 D012757
650    _2
$a léky rostlinné čínské $x farmakologie $x aplikace a dávkování $7 D004365
650    _2
$a oocysty $x účinky léků $7 D033661
650    _2
$a kokcidiostatika $x farmakologie $x aplikace a dávkování $7 D003049
650    _2
$a Eimeria $x účinky léků $x fyziologie $7 D004539
650    _2
$a triaziny $x farmakologie $x aplikace a dávkování $7 D014227
655    _2
$a časopisecké články $7 D016428
700    1_
$a Wang, Zhanming $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
700    1_
$a Li, Shijie $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
700    1_
$a Chen, Pan $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
700    1_
$a Liu, Kaili $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
700    1_
$a Li, Manman $u Henan Zhongyang Animal Husbandry Co. Ltd., China
700    1_
$a Wang, Yingmin $u Henan Zhongyang Animal Husbandry Co. Ltd., China
700    1_
$a Shaukat, Aftab $u National Center for International Research on Animal Genetics, Breeding and Reproduction (NCIRAGBR), Huazhong Agricultural University, Wuhan, China
700    1_
$a Abdullah, Muhammad $u Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Pakistan. # These authors contributed equally. *Corresponding author: Shucheng Huang, E-mail: huang.sc@henau.edu.cn, ORCID: 0000-0003-3163-8616; Fuchun Jian, E-mail: jfchun2008@163.com, ORCID: 0000-0001-9481-2277. Address for correspondence: College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
700    1_
$a Li, Senyang $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
700    1_
$a Huang, Shucheng $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China $1 https://orcid.org/0000000331638616
700    1_
$a Jian, Fuchun $u College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China $1 https://orcid.org/0000000194812277
773    0_
$w MED00011006 $t Folia parasitologica $x 1803-6465 $g Roč. 71 (20240417)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/38813809 $y Pubmed
910    __
$a ABA008 $b online $c $y - $z 0
990    __
$a 20250107 $b ABA008
991    __
$a 20250110092626 $b ABA008
999    __
$a kom $b bmc $g 2247198 $s 1236313
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 71 $c - $e 20240417 $i 1803-6465 $m Folia parasitologica $n Folia Parasitol (Praha) $x MED00011006
LZP    __
$a Pubmed-20250107
Back

Find record

Citation metrics

Archiving options