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International consensus recommendations on face transplantation: A 2-step Delphi study

B. Longo, FB. Alberti, B. Pomahac, JJ. Pribaz, JP. Meningaud, B. Lengelé, Ö. Özkan, Ö. Özkan, JP. Barret, P. Lassus, P. Blondeel, N. Roche, R. Gurunian, P. Infante-Cossio, A. Lindford, G. Brandacher, P. Giovanoli, J. Plock, VS. Gorantla, ER....

. 2024 ; 24 (1) : 104-114. [pub] 20230902

Language English Country United States

Document type Journal Article

Grant support
MR/S017356/1 Medical Research Council - United Kingdom

Face transplantation is a viable reconstructive approach for severe craniofacial defects. Despite the evolution witnessed in the field, ethical aspects, clinical and psychosocial implications, public perception, and economic sustainability remain the subject of debate and unanswered questions. Furthermore, poor data reporting and sharing, the absence of standardized metrics for outcome evaluation, and the lack of consensus definitions of success and failure have hampered the development of a "transplantation culture" on a global scale. We completed a 2-round online modified Delphi process with 35 international face transplant stakeholders, including surgeons, clinicians, psychologists, psychiatrists, ethicists, policymakers, and researchers, with a representation of 10 of the 19 face transplant teams that had already performed the procedure and 73% of face transplants. Themes addressed included patient assessment and selection, indications, social support networks, clinical framework, surgical considerations, data on patient progress and outcomes, definitions of success and failure, public image and perception, and financial sustainability. The presented recommendations are the product of a shared commitment of face transplant teams to foster the development of face transplantation and are aimed at providing a gold standard of practice and policy.

AboutFace University of York UK

Center for Global Health Ethics Duquesne University Pittsburgh Pennsylvania USA

Chair of Plastic Surgery Department of Surgical Sciences Tor Vergata University of Rome Rome Italy

Department of Communication University of Pittsburgh Pittsburgh Pennsylvania USA

Department of Maxillofacial Surgery Sant'Andrea Hospital Sapienza University of Rome Rome Italy

Department of Oral and Maxillofacial Surgery Virgen del Rocio University Hospital University of Seville Seville Spain

Department of Plastic and Reconstructive Surgery Akdeniz University School of Medicine Antalya Turkey

Department of Plastic and Reconstructive Surgery Cliniques Universitaires Saint Luc Brussels Belgium

Department of Plastic and Reconstructive Surgery Ghent University Hospital Ghent Belgium

Department of Plastic and Reconstructive Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA

Department of Plastic and Reconstructive Surgery Morsani College of Medicine University of South Florida Tampa Florida USA

Department of Plastic and Reconstructive Surgery The Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne UK

Department of Plastic and Reconstructive Surgery Università degli Studi di Napoli Federico 2 Napoli Italy

Department of Plastic Reconstructive and Maxillofacial Surgery Henri Mondor Hospital University of Paris Créteil France

Department of Plastic Surgery and Burns Vall d'Hebron Barcelona Hospital Campus Universidad Autònoma de Barcelona Barcelona Spain

Department of Plastic Surgery and Hand Surgery University Hospital Zurich Zurich Switzerland

Department of Plastic Surgery Cleveland Clinic Abu Dhabi Abu Dhabi United Arab Emirates

Department of Plastic Surgery Helsinki University Hospital University of Helsinki Helsinki Finland

Department of Plastic Surgery Leeds Teaching Hospitals Leeds UK

Department of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA

Department of Surgery Wake Forest School of Medicine Wake Forest Institute of Regenerative Medicine Winston Salem North Carolina USA

Director of Interface and Director of the Centre for Technology and the Body King's College London

Director of National Transplants Center National Institute of Health Italian Ministry of Health Rome Italy

Division of Anesthesia and Intensive Care Medicine Department of Clinical and Surgical Translational Medicine Sant'Andrea Hospital Sapienza University of Rome Rome Italy

Division of Plastic and Reconstructive Surgery Department of Surgery Yale New Haven Hospital Yale School of Medicine New Haven Connecticut USA

Liver Transplant Unit Freeman Hospital Newcastle Hospitals NHS Foundation Trust Newcastle University Newcastle UK

NHS Blood and Transplant Stoke Gifford Bristol UK

School of Psychology Universidad Panamericana Benito Juárez Mexico City Mexico

References provided by Crossref.org

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