Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Gut Microbiome and Pulmonary Arterial Hypertension - A Novel and Evolving Paradigm

T. Thenappan, EK. Weir

. 2024 ; 73 (Suppl. 2) : S477-S485. [pub] 20241129

Status minimal Language English Country Czech Republic

Document type Journal Article, Review

Persistent link   https://www.medvik.cz/link/bmc25005532

Pulmonary arterial hypertension is characterized by perivascular and systemic inflammation. The gut microbiome influences the host immune system. Here we review the emerging preclinical and clinical evidence that strongly suggests that alterations in the gut microbiome may either initiate or facilitate progression of established pulmonary arterial hypertension by modifying the systemic immune responses. We also briefly review the relationship between the gut microbiome and preeclampsia, a vascular disease also characterized by inflammation. Key words: Dysbiosis, Right ventricle, Inflammation.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc25005532
003      
CZ-PrNML
005      
20250312151246.0
007      
ta
008      
250213s2024 xr f 000 0|eng||
009      
AR
024    7_
$a 10.33549/physiolres.935430 $2 doi
035    __
$a (PubMed)39589297
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Thenappan, T $u Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA. tthenapp@umn.edu
245    10
$a Gut Microbiome and Pulmonary Arterial Hypertension - A Novel and Evolving Paradigm / $c T. Thenappan, EK. Weir
520    9_
$a Pulmonary arterial hypertension is characterized by perivascular and systemic inflammation. The gut microbiome influences the host immune system. Here we review the emerging preclinical and clinical evidence that strongly suggests that alterations in the gut microbiome may either initiate or facilitate progression of established pulmonary arterial hypertension by modifying the systemic immune responses. We also briefly review the relationship between the gut microbiome and preeclampsia, a vascular disease also characterized by inflammation. Key words: Dysbiosis, Right ventricle, Inflammation.
650    _2
$a lidé $7 D006801
650    12
$a střevní mikroflóra $x fyziologie $7 D000069196
650    _2
$a zvířata $7 D000818
650    12
$a dysbióza $7 D064806
650    12
$a plicní arteriální hypertenze $x mikrobiologie $x patofyziologie $7 D000081029
650    _2
$a těhotenství $7 D011247
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a preeklampsie $x mikrobiologie $x patofyziologie $x imunologie $7 D011225
650    _2
$a zánět $x mikrobiologie $x imunologie $7 D007249
650    _2
$a plicní hypertenze $x mikrobiologie $x patofyziologie $7 D006976
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Weir, E K
773    0_
$w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 73, Suppl. 2 (2024), s. S477-S485
856    41
$u https://pubmed.ncbi.nlm.nih.gov/39589297 $y Pubmed
910    __
$a ABA008 $b A 4120 $c 266 $y - $z 0
990    __
$a 20250213 $b ABA008
991    __
$a 20250312151253 $b ABA008
999    __
$a min $b bmc $g 2283568 $s 1242552
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 73 $c Suppl. 2 $d S477-S485 $e 20241129 $i 1802-9973 $m Physiological research $n Physiol Res $x MED00003824
LZP    __
$a Pubmed-20250213

Find record

Citation metrics

Archiving options