• Something wrong with this record ?

Impact of Anthropometric Measures on Distal vs Conventional Radial Access for Percutaneous Coronary Procedures

GA. Sgueglia, A. Aminian, M. Wiemer, J. Kefer, GL. Gasparini, Z. Ruzsa, MAH. van Leeuwen, C. Ungureanu, G. Leibundgut, B. Vandeloo, S. Kedev, I. Bernat, K. Ratib, JF. Iglesias, E. Al Hage, S. Saito

. 2025 ; 4 (2) : 101565. [pub] 20250113

Status not-indexed Language English Country United States

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc25008511

BACKGROUND: Results from the Distal vs Conventional Radial Access (DISCO RADIAL) trial confirmed distal radial access (DRA) as a valid alternative to conventional transradial access, with equally low rates of radial artery occlusion (RAO), yet higher crossovers but shorter hemostasis. OBJECTIVES: The purpose of the study was to investigate whether patient anthropometric measures influence the effect of randomized access on key secondary outcomes. METHODS: DISCO RADIAL was an international, multicenter, randomized controlled trial in which patients with indications for percutaneous coronary procedure using a 6-F Slender sheath were randomized to DRA (n = 650) or transradial access (n = 657) implementing best practices to reduce RAO. The primary endpoint of the trial was incidence of forearm RAO, which was extremely uncommon. Secondary endpoints, including sheath insertion time, radial artery spasm, crossover (failure to obtain access through assigned access site), hemostasis time, and access site complications, were the focus of the current analysis. Regression models (linear for continuous and logistic for binary outcomes) were used to determine whether anthropometric measures (weight, height, body mass index, and body surface area) influenced the effect of randomized access on outcomes. RESULTS: Across tertiles of weight, height, body mass index, and body surface area, both before and after adjustment for sex and age, the main effect of vascular access on radial artery spasm, crossover, hemostasis time, and access site complications remained, with no significant interaction effect. CONCLUSIONS: The results of this exploratory analysis are consistent with the main findings of the trial and support the use of DRA in all patients, regardless of anthropometric measures.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc25008511
003      
CZ-PrNML
005      
20250422095813.0
007      
ta
008      
250408s2025 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.jacadv.2024.101565 $2 doi
035    __
$a (PubMed)39898346
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Sgueglia, Gregory A $u Division of Cardiology, Sant'Eugenio Hospital, Rome, Italy
245    10
$a Impact of Anthropometric Measures on Distal vs Conventional Radial Access for Percutaneous Coronary Procedures / $c GA. Sgueglia, A. Aminian, M. Wiemer, J. Kefer, GL. Gasparini, Z. Ruzsa, MAH. van Leeuwen, C. Ungureanu, G. Leibundgut, B. Vandeloo, S. Kedev, I. Bernat, K. Ratib, JF. Iglesias, E. Al Hage, S. Saito
520    9_
$a BACKGROUND: Results from the Distal vs Conventional Radial Access (DISCO RADIAL) trial confirmed distal radial access (DRA) as a valid alternative to conventional transradial access, with equally low rates of radial artery occlusion (RAO), yet higher crossovers but shorter hemostasis. OBJECTIVES: The purpose of the study was to investigate whether patient anthropometric measures influence the effect of randomized access on key secondary outcomes. METHODS: DISCO RADIAL was an international, multicenter, randomized controlled trial in which patients with indications for percutaneous coronary procedure using a 6-F Slender sheath were randomized to DRA (n = 650) or transradial access (n = 657) implementing best practices to reduce RAO. The primary endpoint of the trial was incidence of forearm RAO, which was extremely uncommon. Secondary endpoints, including sheath insertion time, radial artery spasm, crossover (failure to obtain access through assigned access site), hemostasis time, and access site complications, were the focus of the current analysis. Regression models (linear for continuous and logistic for binary outcomes) were used to determine whether anthropometric measures (weight, height, body mass index, and body surface area) influenced the effect of randomized access on outcomes. RESULTS: Across tertiles of weight, height, body mass index, and body surface area, both before and after adjustment for sex and age, the main effect of vascular access on radial artery spasm, crossover, hemostasis time, and access site complications remained, with no significant interaction effect. CONCLUSIONS: The results of this exploratory analysis are consistent with the main findings of the trial and support the use of DRA in all patients, regardless of anthropometric measures.
590    __
$a NEINDEXOVÁNO
655    _2
$a časopisecké články $7 D016428
700    1_
$a Aminian, Adel $u Department of Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium
700    1_
$a Wiemer, Marcus $u Department of Cardiology and Intensive Care, Johannes Wesling University Hospital Ruhr University Bochum, Minden, Germany
700    1_
$a Kefer, Joëlle $u Division of Cardiology, Cliniques Universitaires Saint-Luc, Brussels, Belgium
700    1_
$a Gasparini, Gabriele L $u Cardio Center, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy
700    1_
$a Ruzsa, Zoltan $u Invasive Cardiology Division, Internal Medicine Department, University of Szeged, Szeged, Hungary $u Cardiac and Vascular Center, Semmelweis University, Budapest, Hungary
700    1_
$a van Leeuwen, Maarten A H $u Department of Cardiology, Isala Heart Center, Zwolle, the Netherlands
700    1_
$a Ungureanu, Claudiu $u Department of Cardiology, Jolimont Hospital, La Louvière, Belgium
700    1_
$a Leibundgut, Gregor $u University Heart Center, University Hospital Basel, Basel, Switzerland
700    1_
$a Vandeloo, Bert $u Department of Cardiology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium
700    1_
$a Kedev, Sasko $u Interventional Cardiology Department, University Clinic of Cardiology, Skopje, Macedonia
700    1_
$a Bernat, Ivo $u Department of Cardiology, University Hospital and Faculty of Medicine Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Ratib, Karim $u Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Keele, United Kingdom
700    1_
$a Iglesias, Juan F $u Department of Cardiology, Geneva University Hospitals, Geneva, Switzerland
700    1_
$a Al Hage, Elias $u Department of Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium
700    1_
$a Saito, Shigeru $u Department of Cardiology, Shonan Kamakura General Hospital, Kanagawa, Japan
773    0_
$w MED00215007 $t JACC: Advances $x 2772-963X $g Roč. 4, č. 2 (2025), s. 101565
856    41
$u https://pubmed.ncbi.nlm.nih.gov/39898346 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20250408 $b ABA008
991    __
$a 20250422095814 $b ABA008
999    __
$a ok $b bmc $g 2306402 $s 1245586
BAS    __
$a 3
BAS    __
$a PreBMC-PubMed-not-MEDLINE
BMC    __
$a 2025 $b 4 $c 2 $d 101565 $e 20250113 $i 2772-963X $m JACC: Advances $n JACC Adv $x MED00215007
LZP    __
$a Pubmed-20250408

Find record

Citation metrics

Archiving options