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Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration
JC. Galofré, JJ. Díez, R. Attanasio, EV. Nagy, R. Negro, E. Papini, P. Perros, M. Žarković, E. Akarsu, M. Alevizaki, G. Ayvaz, T. Bednarczuk, BN. Beleslin, E. Berta, M. Bodor, AM. Borissova, M. Boyanov, C. Buffet, MC. Burlacu, H. Dobnig, V....
Jazyk angličtina Země Itálie
Typ dokumentu časopisecké články
- MeSH
- dospělí MeSH
- hormony štítné žlázy * krev MeSH
- hypotyreóza epidemiologie terapie farmakoterapie MeSH
- lékařská praxe - způsoby provádění statistika a číselné údaje normy MeSH
- lidé středního věku MeSH
- lidé MeSH
- obezita * epidemiologie terapie MeSH
- průzkumy a dotazníky MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Evropa MeSH
PURPOSE: The use of thyroid hormones (TH) to treat obesity is unsupported by evidence as reflected in international guidelines. We explored views about this practice, and associations with respondent characteristics among European thyroid specialists. METHODS: Specialists from 28 countries were invited to a survey via professional organisations. The relevant question was whether "Thyroid hormones may be indicated in biochemically euthyroid patients with obesity resistant to lifestyle interventions". RESULTS: Of 17,232 invitations 5695 responses were received (33% valid response rate; 65% women; 90% endocrinologists). Of these, 290 (5.1%) stated that TH may be indicated as treatment for obesity in euthyroid patients. This view was commoner among non-endocrinologists (8.7% vs. 4.7%, p < 0.01), private practice (6.5% vs. 4.5%, p < 0.01), and varied geographically (Eastern Europe, 7.3%; Southern Europe, 4.8%; Western Europe, 2.7%; and Northern Europe, 2.5%). Respondents from Northern and Western Europe were less likely to use TH than those from Eastern Europe (p < 0.01). Gross national income (GNI) correlated inversely with this view (OR 0.97, CI: 0.96-0.97; p < 0.001). Having national guidelines on hypothyroidism correlated negatively with treating obesity with TH (OR 0.71, CI: 0.55-0.91). CONCLUSIONS: Despite the lack of evidence, and contrary to guidelines' recommendations, about 5% of respondents stated that TH may be indicated as a treatment for obesity in euthyroid patients resistant to life-style interventions. This opinion was associated with (i) respondent characteristics: being non-endocrinologist, working in private practice, treating a small number of hypothyroid patients annually and (ii) national characteristics: prevalence of obesity, Eastern Europe, low GNI and lack of national hypothyroidism guidelines.
Cabinet Médical 2 Rue Bellefontaine Lausanne Switzerland
Clinic of Endocrinology and Metabolism University Hospital Alexandrovska Sofia Bulgaria
Department of Endocrinology and Diabetes Centre Hellenic Red Cross Hospital Athens Greece
Department of Endocrinology and Metabolism Koru Ankara Hospital Kizilirmak Ankara Turkey
Department of Endocrinology and Metabolism Regina Apostolorum Hospital Rome Italy
Department of Endocrinology Belarusian State Medical University Minsk Republic of Belarus
Department of Endocrinology Carol Davila University of Medicine and Pharmacy Bucharest Romania
Department of Endocrinology Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain
Department of Endocrinology Odense University Hospital Odense Denmark
Department of Endocrinology Skåne University Hospital Malmö Sweden
Department of Endocrinology Tampere University Hospital Tampere Finland
Department of Internal Medicine and Endocrinology Medical University of Warsaw Warsaw Poland
Department of Internal Medicine Medical University Sofia Sofia Bulgaria
Department of Medicine Universidad Autónoma de Madrid Madrid Spain
Department of Surgery Tampere University Hospital Tampere Finland
Diabetes and Endocrinology Section Beacon Hospital Beacon Court Dublin Ireland
Division of Endocrinology 5 Fazzi Hospital Lecce Italy
Division of Endocrinology Diabetes and Metabolism University of Lausanne Lausanne Switzerland
East Surrey Hospital Surrey and Sussex Healthcare NHS Trust Redhill Surrey UK
Faculty of Medicine University of Belgrade Belgrade Serbia
Institute of Translational and Clinical Research Newcastle University Newcastle Upon Tyne UK
Instituto de Investigación Sanitaria de Navarra Pamplona Spain
Instituto de Investigación Sanitaria Puerta de Hierro Segovia de Arana Majadahonda Madrid Spain
Robert Graves Institute Tallaght University Hospital Dublin Ireland
School of Medicine University College Dublin Dublin Ireland
Scientific Committee Associazione Medici Endocrinologi Milan Italy
Thyroid and Osteoporosis Praxis Kumberg Austria
Thyroid Practice for Radiofrequency Ablation Vienna Austria
Thyroid Task Force From the Sociedad Española de Endocrinología y Nutrición Madrid Spain
Citace poskytuje Crossref.org
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- $a Galofré, J C $u Department of Endocrinology and Nutrition, Clínica Universidad de Navarra, Pío XII, 36., 31080, Pamplona, Spain. jcgalofre@unav.es $u Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain. jcgalofre@unav.es $u Thyroid Task Force From the Sociedad Española de Endocrinología y Nutrición (SEEN), Madrid, Spain. jcgalofre@unav.es $1 https://orcid.org/0000000302273566
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- $a Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration / $c JC. Galofré, JJ. Díez, R. Attanasio, EV. Nagy, R. Negro, E. Papini, P. Perros, M. Žarković, E. Akarsu, M. Alevizaki, G. Ayvaz, T. Bednarczuk, BN. Beleslin, E. Berta, M. Bodor, AM. Borissova, M. Boyanov, C. Buffet, MC. Burlacu, H. Dobnig, V. Fadeyev, BCT. Field, E. Fliers, D. Führer, T. Hakala, J. Jiskra, P. Kopp, M. Krebs, M. Kršek, M. Kužma, M. Lantz, I. Lazúrová, L. Leenhardt, V. Luchytskiy, FM. Puga, A. McGowan, S. Metso, C. Moran, T. Morgunova, DA. Niculescu, B. Perić, T. Planck, C. Poiana, E. Robenshtok, PO. Rosselet, M. Ruchala, KR. Riis, A. Shepelkevich, M. Tronko, D. Unuane, I. Vardarli, WE. Visser, M. Vryonidou, YR. Younes, L. Hegedüs
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