-
Je něco špatně v tomto záznamu ?
Insights from ADPedKD, ERKReg and RaDaR registries provide a multi-national perspective on the presentation of childhood autosomal dominant polycystic kidney disease in high- and middle-income countries
C. Gimpel, S. Fieuws, J. Hofstetter, D. Pitcher, L. Vanmeerbeek, S. Haeberle, A. Dachy, L. Massella, T. Seeman, B. Ranchin, L. Allard, J. Bacchetta, US. Bayrakci, F. Becherucci, V. Perez-Beltran, M. Besouw, H. Bialkevich, O. Boyer, N. Canpolat,...
Jazyk angličtina Země Spojené státy americké
Typ dokumentu srovnávací studie, časopisecké články, multicentrická studie
NLK
Freely Accessible Science Journals
od 1972
Open Access Digital Library
od 1972-01-01
- MeSH
- dítě MeSH
- genetické testování statistika a číselné údaje ekonomika MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- polycystické ledviny autozomálně dominantní * diagnóza epidemiologie genetika ekonomika MeSH
- předškolní dítě MeSH
- prenatální diagnóza MeSH
- registrace MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- srovnávací studie MeSH
- Geografické názvy
- Evropa MeSH
- Spojené království MeSH
Data on the presentation of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in children have been based on small/regional cohorts and practices regarding both asymptomatic screening in minors and genetic testing differ greatly between countries. To provide a global perspective, we analyzed over 2100 children and adolescents with ADPKD from 32 countries in six World Health Organization regions: 1060 children from the multi-national ADPedKD registry were compared to 269 pediatric patients from the United Kingdom (RaDaR) and 825 from the European Rare Kidney Disease Registry (ERKReg). Asymptomatic family screening was a common mode of presentation (48% in ADPedKD, 62% in ERKReg) with broad international variability (19%-75%), but fairly stable temporal trends in both registries with no correlation to genetic testing. The national rates of genetic testing varied and correlated significantly with healthcare expenditure (odds ratio 1.030 per 100 United States Dollars/capita/year, in the ERKReg cohort), with little variation over time. Diagnosis due to prenatal abnormalities was more common than anticipated at 14% increasing steadily from 2000 onward in both registries. Realistically, a high proportion of children were diagnosed with ADPKD by active screening, underlining that families affected by ADPKD have a high need for counselling on the complex issues around presymptomatic diagnosis. Regional variations in rate of genetic testing appeared to be driven by economic factors. However, large differences in rate of active screening were not correlated to healthcare spending and probably reflect the influence of different of cultural, legal and ethical frameworks on families and clinicians in different healthcare systems.
1st Department of Childhood Diseases Belarusian State Medical University Minsk Republic of Belarus
Biostatistics and Statistical Bioinformatics Center KU Leuven Leuven Belgium
Center de Reference de Maladie Rares du Sud Ouest SORAR CHU Toulouse Toulouse France
College of Medicine and Dentistry James Cook University Townsville Australia
Department of Biomedical Experimental and Clinical Sciences University of Florence Florence Italy
Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton Ontario Canada
Department of General Pediatrics University Children's Hospital Münster Münster Germany
Department of Internal Medicine and Pediatrics Ghent University Ghent Belgium
Department of Medical Translational Sciences University of Campania Naples Italy
Department of Nephrology and Transplantation Beaumont Hospital Dublin Ireland
Department of Nephrology Institute for Mother and Child Health Care Belgrade Serbia
Department of Paediatrics University Medical Centre Maribor Maribor Slovenia
Department of Pediatric Nephrology and Hypertension Medical University of Gdańsk Gdańsk Poland
Department of Pediatric Nephrology Ghent University Hospital Ghent Belgium
Department of Pediatric Nephrology University Hospital Leuven Leuven Belgium
Department of Pediatrics 2nd Medical Faculty Charles University Prague Prague Czech Republic
Department of Pediatrics FMS in Zabrze Medical University of Silesia Katowice Poland
Department of Pediatrics Medical Faculty University of Ostrava Ostrava Czech Republic
Department of Pediatrics ULiège Academic Hospital Liège Belgium
Department of Renal Medicine Townsville University Hospital Townsville Australia
Department of Renal Medicine University College London London UK
Division of Human Genetics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA
Division of Nephrology Bambino Gesù Children's Hospital IRCCS Rome Italy
Division of Nephrology Children's Hospital of Philadelphia Philadelphia Pennsylvania USA
Division of Pediatric Nephrology Center for Pediatrics and Adolescent Medicine Heidelberg Germany
Division of Pediatric Nephrology Medical Faculty Marmara University Istanbul Turkey
Divison of Nephrology Saint Luc Academic Hospital Brussels Belgium
Institut Necker Enfants Malades INSERM U1151 Université Paris Cité Paris France
Institute for Molecular Bioscience the University of Queensland Brisbane Australia
Louvain Medical School Université Catholique de Louvain Louvain Belgium
National Registry of Rare Kidney Diseases Bristol UK
Nephrology and Dialysis Unit Meyer Children's Hospital IRCCS Florence Italy
Paediatric Nephrology Department University Hospital Vall d'Hebron Barcelona Spain
Pediatric Center Institute of Clinical Medicine Vilnius University Vilnius Lithuania
Pediatric Nephrology Department Hospital Universitario Santa Lucía Cartagena Spain
Pediatric Nephrology Department Robert Debre Hospital APHP Paris France
Pediatric Nephrology Fundeni Clinical Institute Bucharest Romania
Pediatric Nephrology Montpellier University Hospital SORARE Reference Center Montpellier France
Pediatric Nephrology Pediatric Unit IRCCS Azienda Ospedaliero Universitaria di Bologna Bologna Italy
Pediatric Nephrology Unit CHU La Réunion Saint Denis France
Pediatric Nephrology Unit Department of Pediatrics University of Geneva Hospital Geneva Switzerland
Peditaric Nephrology Unit Regina Margherita Children's Hospital Turin Italy
Service de Néphrologie Adulte Hôpital Rangueil University Hospital Toulouse France
Service de Nephrologie Adultes AP HP Hôpital Necker Paris France
Service de Pédiatrie 2 CHU Besançon Besançon France
Service de Pédiatrie CHC MontLégia Liège Belgium
The KidGen Collaborative Australian Genomics Melbourne Australia
Unit of Nephrology Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII Bergamo Italy
University of Belgrade Faculty of Medicine University Children's Hospital Belgrade Serbia
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc25015215
- 003
- CZ-PrNML
- 005
- 20250731090834.0
- 007
- ta
- 008
- 250708s2025 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.kint.2025.02.026 $2 doi
- 035 __
- $a (PubMed)40122340
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Gimpel, Charlotte $u Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany
- 245 10
- $a Insights from ADPedKD, ERKReg and RaDaR registries provide a multi-national perspective on the presentation of childhood autosomal dominant polycystic kidney disease in high- and middle-income countries / $c C. Gimpel, S. Fieuws, J. Hofstetter, D. Pitcher, L. Vanmeerbeek, S. Haeberle, A. Dachy, L. Massella, T. Seeman, B. Ranchin, L. Allard, J. Bacchetta, US. Bayrakci, F. Becherucci, V. Perez-Beltran, M. Besouw, H. Bialkevich, O. Boyer, N. Canpolat, D. Chauveau, N. Çiçek, PJ. Conlon, O. Devuyst, C. Dossier, M. Fila, H. Flögelová, A. Godron-Dubrasquet, I. Gokce, EG. Nguyen-Tang, JD. González-Rodríguez, A. Guffens, G. Grandaliano, L. Heidet, A. Jankauskiene, TK. Levart, B. Knebelmann, JC. König, C. La Scola, VF. Leone, V. Leroy, M. Litwin, L. Lucchetti, AC. Lungu, P. Marzuillo, A. Mastrangelo, M. Miklaszewska, G. Montini, F. Nobili, L. Obrycki, S. Papizh, A. Paripović, D. Paripović, L. Peruzzi, A. Raes, S. Saygili, B. Spasojević, T. Simon, M. Szczepańska, F. Trepiccione, NM. Varda, R. Westland, S. Yüksel, I. Zaluska-Lesniewska, J. Tenebaum, R. Mustafa, AJ. Mallett, LM. Guay-Woodford, DP. Gale, D. Böckenhauer, MC. Liebau, F. Schaefer, D. Mekahli, RaDaR ADPKD Rare Disease Group, ERKReg Collaborators, ADPedKD Collaborators
- 520 9_
- $a Data on the presentation of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in children have been based on small/regional cohorts and practices regarding both asymptomatic screening in minors and genetic testing differ greatly between countries. To provide a global perspective, we analyzed over 2100 children and adolescents with ADPKD from 32 countries in six World Health Organization regions: 1060 children from the multi-national ADPedKD registry were compared to 269 pediatric patients from the United Kingdom (RaDaR) and 825 from the European Rare Kidney Disease Registry (ERKReg). Asymptomatic family screening was a common mode of presentation (48% in ADPedKD, 62% in ERKReg) with broad international variability (19%-75%), but fairly stable temporal trends in both registries with no correlation to genetic testing. The national rates of genetic testing varied and correlated significantly with healthcare expenditure (odds ratio 1.030 per 100 United States Dollars/capita/year, in the ERKReg cohort), with little variation over time. Diagnosis due to prenatal abnormalities was more common than anticipated at 14% increasing steadily from 2000 onward in both registries. Realistically, a high proportion of children were diagnosed with ADPKD by active screening, underlining that families affected by ADPKD have a high need for counselling on the complex issues around presymptomatic diagnosis. Regional variations in rate of genetic testing appeared to be driven by economic factors. However, large differences in rate of active screening were not correlated to healthcare spending and probably reflect the influence of different of cultural, legal and ethical frameworks on families and clinicians in different healthcare systems.
- 650 _2
- $a mladiství $7 D000293
- 650 _2
- $a dítě $7 D002648
- 650 _2
- $a předškolní dítě $7 D002675
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a kojenec $7 D007223
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a genetické testování $x statistika a číselné údaje $x ekonomika $7 D005820
- 650 12
- $a polycystické ledviny autozomálně dominantní $x diagnóza $x epidemiologie $x genetika $x ekonomika $7 D016891
- 650 _2
- $a prenatální diagnóza $7 D011296
- 650 _2
- $a registrace $7 D012042
- 651 _2
- $a Evropa $x epidemiologie $7 D005060
- 651 _2
- $a Spojené království $x epidemiologie $7 D006113
- 655 _2
- $a srovnávací studie $7 D003160
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a multicentrická studie $7 D016448
- 700 1_
- $a Fieuws, Steffen $u PKD Research Group, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium; Biostatistics and Statistical Bioinformatics Center, KU Leuven, Leuven, Belgium
- 700 1_
- $a Hofstetter, Jonas $u Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany
- 700 1_
- $a Pitcher, David $u Department of Renal Medicine, University College London, London, UK; National Registry of Rare Kidney Diseases, Bristol, UK
- 700 1_
- $a Vanmeerbeek, Lotte $u PKD Research Group, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium; Department of Pediatric Nephrology, University Hospital Leuven, Leuven, Belgium
- 700 1_
- $a Haeberle, Stefanie $u Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany
- 700 1_
- $a Dachy, Angélique $u PKD Research Group, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium; Department of Pediatric Nephrology, University Hospital Leuven, Leuven, Belgium; Department of Pediatrics, ULiège Academic Hospital, Liège, Belgium
- 700 1_
- $a Massella, Laura $u Division of Nephrology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy
- 700 1_
- $a Seeman, Tomas $u Department of Pediatrics, 2nd Medical Faculty, Charles University Prague, Prague, Czech Republic; Department of Pediatrics, Medical Faculty, University of Ostrava, Ostrava, Czech Republic
- 700 1_
- $a Ranchin, Bruno $u Pediatric Nephrology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, INSERM1033 Research Unit, Université de Lyon, European Rare Kidney Disease Reference Network Center, Lyon, France
- 700 1_
- $a Allard, Lise $u Reference Center for Rare Kidney Diseases (SoRare), ERKNet, Department of Pediatrics, Bordeaux University Hospital, Bordeaux, France
- 700 1_
- $a Bacchetta, Justine $u Pediatric Nephrology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, INSERM1033 Research Unit, Université de Lyon, European Rare Kidney Disease Reference Network Center, Lyon, France
- 700 1_
- $a Bayrakci, Umut S $u Department of Paediatric Nephrology, Ankara City Hospital, Üniversiteler Mahallesi Bilkent Caddesi, Çankaya/Ankara, Turkey
- 700 1_
- $a Becherucci, Francesca $u Nephrology and Dialysis Unit, Meyer Children's Hospital IRCCS, Florence, Italy; Department of Biomedical Experimental and Clinical Sciences, University of Florence, Florence, Italy
- 700 1_
- $a Perez-Beltran, Victor $u Paediatric Nephrology Department, University Hospital Vall d'Hebron, Barcelona, Spain
- 700 1_
- $a Besouw, Martine $u Department of Pediatric Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
- 700 1_
- $a Bialkevich, Hanna $u 1st Department of Childhood Diseases, Belarusian State Medical University, Minsk, Republic of Belarus
- 700 1_
- $a Boyer, Olivia $u LH, Service de Néphrologie Pédiatrique, Centre de Référence MARHEA, Hôpital Universitaire Necker-Enfants Malades, Assistance publique, Hôpitaux de Paris (AP-HP), Paris, France; Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Institut Imagine, Université de Paris-Cité, Paris, France
- 700 1_
- $a Canpolat, Nur $u Department of Paediatric Nephrology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey
- 700 1_
- $a Chauveau, Dominique $u Service de Néphrologie Adulte - Hôpital Rangueil, University Hospital, Toulouse, France
- 700 1_
- $a Çiçek, Neslihan $u Division of Pediatric Nephrology, Medical Faculty, Marmara University, Istanbul, Turkey
- 700 1_
- $a Conlon, Peter J $u Department of Nephrology and Transplantation, Beaumont Hospital, Dublin, Ireland
- 700 1_
- $a Devuyst, Olivier $u Louvain Medical School, Université Catholique de Louvain, Louvain, Belgium; Divison of Nephrology, Saint-Luc Academic Hospital, Brussels, Belgium
- 700 1_
- $a Dossier, Claire $u Pediatric Nephrology Department, Robert-Debre Hospital, APHP, Paris, France
- 700 1_
- $a Fila, Marc $u Pediatric Nephrology, Montpellier University Hospital, SORARE Reference Center, Montpellier, France
- 700 1_
- $a Flögelová, Hana $u Department of Pediatrics, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic
- 700 1_
- $a Godron-Dubrasquet, Astrid $u Reference Center for Rare Kidney Diseases (SoRare), ERKNet, Department of Pediatrics, Bordeaux University Hospital, Bordeaux, France
- 700 1_
- $a Gokce, Ibrahim $u Division of Pediatric Nephrology, Medical Faculty, Marmara University, Istanbul, Turkey
- 700 1_
- $a Nguyen-Tang, Elsa Gonzalez $u Pediatric Nephrology Unit, Department of Pediatrics, University of Geneva Hospital, Geneva, Switzerland
- 700 1_
- $a González-Rodríguez, Juan David $u Pediatric Nephrology Department, Hospital Universitario Santa Lucía, Cartagena, Spain
- 700 1_
- $a Guffens, Anne $u Service de Pédiatrie, CHC MontLégia, Liège, Belgium
- 700 1_
- $a Grandaliano, Giuseppe $u Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Nephrology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
- 700 1_
- $a Heidet, Laurence $u LH, Service de Néphrologie Pédiatrique, Centre de Référence MARHEA, Hôpital Universitaire Necker-Enfants Malades, Assistance publique, Hôpitaux de Paris (AP-HP), Paris, France; Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Institut Imagine, Université de Paris-Cité, Paris, France
- 700 1_
- $a Jankauskiene, Augustina $u Pediatric Center, Institute of Clinical Medicine, Vilnius University, Vilnius, Lithuania
- 700 1_
- $a Levart, Tanja Kersnik $u Nephrology Department, University Medical Centre Ljubljana, University Children's Hospital, Ljubljana, Slovenia
- 700 1_
- $a Knebelmann, Bertrand $u Institut Necker Enfants Malades, INSERM U1151, Université Paris Cité, Paris, France; Service de Nephrologie Adultes, AP-HP, Hôpital Necker, Paris, France
- 700 1_
- $a König, Jens Christian $u Department of General Pediatrics, University Children's Hospital Münster, Münster, Germany
- 700 1_
- $a La Scola, Claudio $u Pediatric Nephrology, Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
- 700 1_
- $a Leone, Valentina Fanny $u Unit of Nephrology, Azienda Socio Sanitaria Territoriale (ASST) Papa Giovanni XXIII, Bergamo, Italy
- 700 1_
- $a Leroy, Valérie $u Pediatric Nephrology Unit, CHU La Réunion, Saint Denis, France
- 700 1_
- $a Litwin, Mieczyslaw $u Department of Nephrology, Kidney Transplantation and Arterial Hypertension, the Children's Memorial Health Institute, Warsaw, Poland
- 700 1_
- $a Lucchetti, Laura $u Division of Nephrology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy
- 700 1_
- $a Lungu, Adrian C $u Pediatric Nephrology, Fundeni Clinical Institute, Bucharest, Romania
- 700 1_
- $a Marzuillo, Pierluigi $u Department of Woman, Child and of General and Specialized Surgery, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy
- 700 1_
- $a Mastrangelo, Antonio $u Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS, Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy
- 700 1_
- $a Miklaszewska, Monika $u Department of Paediatric Nephrology and Hypertension, Jagiellonian University, Medical College of Cracow, Cracow, Poland
- 700 1_
- $a Montini, Giovanni $u Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS, Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy; Giuliana and Bernardo Caprotti Chair of Pediatrics, Department of Clinical Sciences and Community Health, University of Milano, Milan, Italy
- 700 1_
- $a Nobili, François $u Service de Pédiatrie 2, CHU Besançon, Besançon, France
- 700 1_
- $a Obrycki, Lukasz $u Department of Nephrology, Kidney Transplantation and Arterial Hypertension, the Children's Memorial Health Institute, Warsaw, Poland
- 700 1_
- $a Papizh, Svetlana $u Veltishev Research Clinical Institute for Pediatrics & Children Surgery, Pirogov Russian National Research Medical University, Moscow, Russia
- 700 1_
- $a Paripović, Aleksandra $u Department of Nephrology, Institute for Mother and Child Health Care, Belgrade, Serbia
- 700 1_
- $a Paripović, Dušan $u University of Belgrade Faculty of Medicine, University Children's Hospital, Belgrade, Serbia
- 700 1_
- $a Peruzzi, Licia $u Peditaric Nephrology Unit, Regina Margherita Children's Hospital, Turin, Italy
- 700 1_
- $a Raes, Ann $u Department of Pediatric Nephrology, Ghent University Hospital, Ghent, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium
- 700 1_
- $a Saygili, Seha $u Department of Paediatric Nephrology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey
- 700 1_
- $a Spasojević, Brankica $u University of Belgrade Faculty of Medicine, University Children's Hospital, Belgrade, Serbia
- 700 1_
- $a Simon, Thomas $u Center de Reference de Maladie Rares du Sud-Ouest SORAR, CHU Toulouse, Toulouse, France
- 700 1_
- $a Szczepańska, Maria $u Department of Pediatrics, FMS in Zabrze, Medical University of Silesia, Katowice, Poland
- 700 1_
- $a Trepiccione, Francesco $u Department of Medical Translational Sciences, University of Campania, Naples, Italy
- 700 1_
- $a Varda, Nataša Marčun $u Department of Paediatrics, University Medical Centre Maribor, Maribor, Slovenia
- 700 1_
- $a Westland, Rik $u Department of Pediatric Nephrology, Amsterdam UMC-Emma Children's Hospital, University of Amsterdam, Amsterdam, the Netherlands
- 700 1_
- $a Yüksel, Selcuk $u Department of Pediatric Nephrology and Pediatric Rheumatology, School of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey
- 700 1_
- $a Zaluska-Lesniewska, Iga $u Department of Pediatric Nephrology and Hypertension, Medical University of Gdańsk, Gdańsk, Poland
- 700 1_
- $a Tenebaum, Julie $u Pediatric Nephrology, Montpellier University Hospital, SORARE Reference Center, Montpellier, France
- 700 1_
- $a Mustafa, Reem $u Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of Nephrology and Hypertension and the Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas, USA
- 700 1_
- $a Mallett, Andrew J $u Department of Renal Medicine, Townsville University Hospital, Townsville, Australia; Institute for Molecular Bioscience, the University of Queensland, Brisbane, Australia; The KidGen Collaborative, Australian Genomics, Melbourne, Australia; College of Medicine and Dentistry, James Cook University, Townsville, Australia
- 700 1_
- $a Guay-Woodford, Lisa M $u Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- 700 1_
- $a Gale, Daniel P $u Department of Renal Medicine, University College London, London, UK; National Registry of Rare Kidney Diseases, Bristol, UK
- 700 1_
- $a Böckenhauer, Detlef $u PKD Research Group, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium; Department of Renal Medicine, University College London, London, UK; Department of Pediatric Nephrology, University Hospital Leuven, Leuven, Belgium
- 700 1_
- $a Liebau, Max C $u Department of Pediatrics and Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
- 700 1_
- $a Schaefer, Franz $u Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany
- 700 1_
- $a Mekahli, Djalila $u PKD Research Group, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium; Department of Pediatric Nephrology, University Hospital Leuven, Leuven, Belgium. Electronic address: djalila.mekahli@uzleuven.be
- 710 2_
- $a RaDaR ADPKD Rare Disease Group
- 710 2_
- $a ERKReg Collaborators
- 710 2_
- $a ADPedKD Collaborators
- 773 0_
- $w MED00010141 $t Kidney international $x 1523-1755 $g Roč. 108, č. 1 (2025), s. 105-118
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/40122340 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y - $z 0
- 990 __
- $a 20250708 $b ABA008
- 991 __
- $a 20250731090829 $b ABA008
- 999 __
- $a ok $b bmc $g 2366208 $s 1252340
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2025 $b 108 $c 1 $d 105-118 $e 20250321 $i 1523-1755 $m Kidney international $n Kidney Int $x MED00010141
- LZP __
- $a Pubmed-20250708
