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Fast Facts: Comprehensive Genomic Profiling : Making precision medicine possible
Bernardo L. Rapoport, Giancarlo Troncone, Fernando Schmitt, Simon Nayler
- Publikováno
- Basel : S. Karger, 2020
- Stránkování
- 108 stran : ilustrace, tabulky
Jazyk angličtina Země Německo
Typ dokumentu příručky
Knihovny.cz ISBN
9783318068191
plný text - pouze pro uživatele NLK
Karger Fast Facts e-book
Knihovny.cz E-zdroje
- MeSH
- genetické techniky MeSH
- genetika MeSH
- genom lidský MeSH
- genotypizační techniky MeSH
- geny nádorové MeSH
- nádorové biomarkery MeSH
- nádory genetika MeSH
- sekvenční analýza DNA MeSH
- Publikační typ
- příručky MeSH
- NLK Obory
- onkologie
- genetika, lékařská genetika
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject.Contents:• Genetic mutations and biomarkers• Understanding next-generation sequencing• Elements of comprehensive genomic profiles• Role in precision oncology• Predictive and prognostic biomarkers• Overcoming barriers to genotype-directed therapy
Comprehensive Genomic Profiling
Print version record
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