Effect of brefeldin A and actinomycin D on culture growth and brefeldin A yield in Curvularia lunata
Language English Country United States Media print
Document type Journal Article
PubMed
565737
DOI
10.1007/bf02915313
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents biosynthesis pharmacology MeSH
- Cyclopentanes biosynthesis pharmacology MeSH
- Dactinomycin pharmacology MeSH
- Glucose metabolism MeSH
- Mitosporic Fungi drug effects growth & development metabolism MeSH
- Mycotoxins biosynthesis pharmacology MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Cyclopentanes MeSH
- Dactinomycin MeSH
- Glucose MeSH
- Mycotoxins MeSH
Cultures incorporated with increasing quantities of brefeldin A in the form of crude extracts of fungal metabolites prior to inoculation demonstrated reduced growth rate and no significant increase in brefeldin A content. On the other hand, cultures incubated with increasing levels of actinomycin D on the 8th day of cultivation showed slight stimulation of brefeldin A formation with insignificant effect on growth.
See more in PubMed
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Folia Microbiol (Praha). 1977;22(1):43-6 PubMed
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