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Effect of malonate and maleate on growth and brefeldin A formation in Curvularia lunata

. 1978 ; 23 (3) : 194-7.

Language English Country United States Media print

Document type Comparative Study, Journal Article

Malonate exerted a stronger inhibitory effect on brefeldin A production than on mycelia growth in cultures of Curvularia lunata especially at inhibitory levels of 100 to 200 mM. The extent of 200 mM malonate inhibition of growth and brefeldin A production was greater in cultures treated with malonate prior to inoculation than those treated following 5 days after inoculation. Maleate at levels of 40 to 220 mM activated brefeldin A formation in cultures though exerting variable effects on mycelia growth.

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