Biosynthesis of fatty acids and sterols in relation to the antibiotic formation in Oudemansiella mucida
Language English Country United States Media print
Document type Comparative Study, Journal Article
PubMed
568102
DOI
10.1007/bf02876440
Knihovny.cz E-resources
- MeSH
- Acetates metabolism MeSH
- Agaricales metabolism MeSH
- Anti-Bacterial Agents biosynthesis MeSH
- Glucose metabolism MeSH
- Fatty Acids biosynthesis MeSH
- Sorbitol metabolism MeSH
- Sterols biosynthesis MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
- Names of Substances
- Acetates MeSH
- Anti-Bacterial Agents MeSH
- Glucose MeSH
- Fatty Acids MeSH
- Sorbitol MeSH
- Sterols MeSH
The production of mucidin by the basidiomycete Oudemansiella mucida was negatively influenced by the application of D-glucitol as the main carbon source, the effect being independent of the growth rate of the mycelium. The rate of fatty acid synthesis was measured by incorporation of 1-14C-acetate. After 8 days of cultivation, the amount of fatty acids was approximately half that synthetized during cultivation on glucose. The specific rate of incorporation reached its maximum after seven days of cultivation. Incorporation of 2-14C-MEValonate into sterols was the same under the two sets of cultivation conditions. Acetate units from the degraded fatty acids are probably also utilized for antibiotic synthesis.
See more in PubMed
Folia Microbiol (Praha). 1969;14(4):377-87 PubMed
Folia Microbiol (Praha). 1976;21(6):488-92 PubMed
Effect of glucitol on the production of mucidin in Oudemansiella mucida
Mucidin-nonproducing mutants of oudemansiella mucida
