The influence of some non-steroidal anti-inflammatory drugs on the retraction of collagen lattices
Jazyk angličtina Země Francie Médium print
Typ dokumentu časopisecké články
PubMed
1820177
DOI
10.1016/0753-3322(91)90047-w
PII: 0753-3322(91)90047-W
Knihovny.cz E-zdroje
- MeSH
- antiflogistika nesteroidní farmakologie MeSH
- fibroblasty chemie MeSH
- kolagen metabolismus MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antiflogistika nesteroidní MeSH
- kolagen MeSH
The effects of some antirheumatics on the formation and retraction of collagen lattices seeded with fibroblasts have been studied. Among the antirheumatics, diclofenac was the most active inhibitor of lattice retraction, then tropesin and to a lesser extent indomethacin. Ibuprofen which is known as a very slight inhibitor of protein synthesis was able to significantly enhance lattice retraction when 10 micrograms/ml (48.5 microM) and 50 micrograms/ml (242 microM) were used.
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