Effect of Tween 80 and dimethyl sulfoxide on biosynthesis of L-lysine in regulatory mutants of Corynebacterium glutamicum
Language English Country United States Media print
Document type Journal Article
PubMed
1841877
DOI
10.1007/bf02884043
Knihovny.cz E-resources
- MeSH
- Corynebacterium drug effects genetics metabolism MeSH
- Dimethyl Sulfoxide pharmacology MeSH
- Lysine biosynthesis MeSH
- Mutation MeSH
- Polysorbates pharmacology MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Dimethyl Sulfoxide MeSH
- Lysine MeSH
- Polysorbates MeSH
By using dimethyl sulfoxide or Tween 80 (1 or 0.2%), the production of L-lysine was increased by 20-28 and 23-25%, respectively, in regulatory mutant strains of Corynebacterium glutamicum. The stimulation observed is supposed to be caused by influencing cellular surface structures.