Effects of drug administration in pregnancy on children's school behaviour
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články
PubMed
1982564
DOI
10.1007/bf01967827
Knihovny.cz E-zdroje
- MeSH
- antipsychotika škodlivé účinky MeSH
- chování dětí účinky léků MeSH
- diazepam škodlivé účinky MeSH
- dítě MeSH
- lékové předpisy MeSH
- lidé MeSH
- školy MeSH
- těhotenství účinky léků MeSH
- zpožděný efekt prenatální expozice * MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- těhotenství účinky léků MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Československo MeSH
- Názvy látek
- antipsychotika MeSH
- diazepam MeSH
Files with prescription data were used to assess possible behavioural changes in children, whose mothers used benzodiazepines or neuroleptic drugs during the second half of their pregnancy. Prescriptions, bearing the identification number of women resident in one district of Prague, filed in pharmacies during 1974 and the first three months of 1975 represent the first part of the data. During 1984, children born in the appropriate earlier period were searched and linked with the earlier prescription data. A group of 68 children with possible exposure to neuroleptics and a group of 15 children possibly exposed to diazepam during the second half of their intrauterine development were found. Two groups of 55 and 7 children, respectively, born of mothers without exposure to these drugs, were chosen as controls. The teachers of classes attended by these children were addressed by a letter and asked to evaluate their behaviour at school. This was done by means of a form containing analogue scales evaluating different features of behaviour. Each child was compared with its control. The statistical evaluation with Student's t-test, regression analysis and analysis of variance did not reveal any significant difference between both groups and their controls.
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