In vitro antigen-binding properties of coelomocytes of Eisenia foetida (Annelida)
Language English Country Netherlands Media print
Document type Journal Article
PubMed
2269488
DOI
10.1016/0165-2478(90)90143-e
PII: 0165-2478(90)90143-E
Knihovny.cz E-resources
- MeSH
- Antigens, Surface immunology MeSH
- Antigens immunology MeSH
- Autoradiography MeSH
- Kinetics MeSH
- Annelida cytology immunology MeSH
- Arsanilic Acid immunology MeSH
- Serum Albumin immunology MeSH
- In Vitro Techniques MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Antigens, Surface MeSH
- Antigens MeSH
- Arsanilic Acid MeSH
- Serum Albumin MeSH
Annelids are capable of cellular and humoral defence reactions against foreign antigens. The main aim of this study was to characterise the antigen-binding properties of coelomocytes of Eisenia foetida by means of quantitative autoradiography and direct measurement of radioactivity. It was found that the antigen-binding capacity was significantly increased after antigen stimulation. Furthermore, the preincubation of coelomocytes with non-labelled proteins reduced the binding of radiolabelled antigen. The highest level of inhibition was found when the same protein was used for preincubation. These results indicate that antigen-binding properties are to some extent specific.
References provided by Crossref.org
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Characterization of the limited specificity of antigen recognition in earthworms