The effect of Hexabrix tracheobronchography on the ultrastructure of the airway epithelium
Jazyk angličtina Země Německo Médium print
Typ dokumentu časopisecké články
PubMed
2392359
DOI
10.1007/bf02075203
Knihovny.cz E-zdroje
- MeSH
- bronchografie * MeSH
- cilie účinky léků ultrastruktura MeSH
- kontrastní látky farmakologie MeSH
- králíci MeSH
- kyselina joxaglová * farmakologie MeSH
- trachea diagnostické zobrazování MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- kontrastní látky MeSH
- kyselina joxaglová * MeSH
The ultrastructure of the airway epithelium was studied after experimental Hexabrix tracheobronchography. Serious damage to the tracheal epithelium due to Hexabrix was recorded. 81 +/- 5% of goblet cells were stimulated to discharge mucus. 43 +/- 3% were completely exhausted and degenerated. The ciliated cells displayed vacuolar degeneration or severe pathological alteration. The average number of cilia/micron 2 fell to 3.3 +/- 0.5. As morphological signs of impaired self-cleaning ability the inspissated mucus and numerous bacteria appeared in the area of the disorganized ciliary border.
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