Koncentrácia kyseliny homovanilovej a 5-hydroxyindoloctovej v CSL u pacientov s loziskovou ischémiou mozgu
[Levels of homovanillic acid and 5-hydroxyindoleacetic acid in the cerebrospinal fluid in patients with focal cerebral ischemia]
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
2483951
- MeSH
- Time Factors MeSH
- Adult MeSH
- Homovanillic Acid cerebrospinal fluid MeSH
- Hydroxyindoleacetic Acid cerebrospinal fluid MeSH
- Middle Aged MeSH
- Humans MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Ischemic Attack, Transient cerebrospinal fluid MeSH
- Age Factors MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Names of Substances
- Homovanillic Acid MeSH
- Hydroxyindoleacetic Acid MeSH
The investigated group comprised 35 patients where clinical examination revealed focal cerebral ischaemia in the area of the a. cerebri media. In the group of elderly patients above 60 years, as compared with controls, the homovanillic acid (HVA) and 5-hydroxyindolacetic acid (5-HIAA) concentration in cerebrospinal fluid was elevated. In the group of patients under 60 years no changes in the concentration of these metabolites were found. In older patients the increased level of metabolites in cerebrospinal fluid persisted also after three days following the attack, while in younger patients the elevated HVA and 5-HIAA levels were found only in specimens collected up to three days.
