Stimulating effect of Streptococcus faecalis on phagocytosis in gnotobiotic piglets
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
2496013
DOI
10.1007/bf02821326
Knihovny.cz E-zdroje
- MeSH
- Enterococcus faecalis imunologie MeSH
- fagocytóza * MeSH
- gnotobiologické modely MeSH
- miniaturní prasata imunologie mikrobiologie MeSH
- monocyty MeSH
- neutrofily MeSH
- novorozená zvířata MeSH
- počet leukocytů veterinární MeSH
- prasata MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
The concentration of active phagocytes in peripheral blood remained in germfree pigs up to the age of one year approximately at the same level as found at the age of 7 d and did not exceed 0.3 X 10(9)/L of blood, whereas a steady increase was established in conventional pigs. Monoassociation of gnotobiotic piglets with Streptococcus faecalis increased during 24 h the concentration of circulating granulocytes and the concentration of active phagocytes. An even more pronounced effect was obtained when formolized S. faecalis cells were applied intraperitoneally to germfree piglets. This treatment elevated the phagocytosis index also in conventional piglets, as well as in germfree piglets previously given cyclophosphamide. Escherichia coli O 83 or a mixture of anaerobic bacteria did not cause any serious changes in the activity of phagocytosis in gnotobiotic piglets. S. faecalis seems to be a natural factor stimulating both the release of granulocytes from their depots as well as their phagocytic activity.
