Experimentální modely zaludecních vredů. Zmĕny v sekreci zaludecních glykoproteinů u vybraných typů
[Experimental models of gastric ulcers. Changes in the secretion of gastric glycoproteins in selected types]
Jazyk čeština Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
2720753
- MeSH
- glykoproteiny metabolismus MeSH
- inbrední kmeny potkanů MeSH
- krysa rodu Rattus MeSH
- žaludeční sliznice metabolismus MeSH
- žaludeční vředy etiologie metabolismus MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- glykoproteiny MeSH
The authors discuss possibilities of modelling of gastric ulcers in experiments on small laboratory animals. In four types of acute gastric ulcers and one type of chronic ulcer changes of glycoproteins in gastric mucus were investigated as to glycoproteins a protective effect on the gastric mucosa is ascribed. As indicator of secretion of these substances total hexose and total protein values were used. It was revealed that in homogenates the total hexose values were in all types of ulcers higher than in the control group. Total protein values were elevated in three types of ulcers. Elevated values of these substances were found also in gastric juice in ulcers after ligature of the pylorus.
