Arachidonic acid-induced inhibition of (Na+K+)-stimulated ATPase in the cerebral cortex and medulla oblongata of young and adult rats
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
2851849
Knihovny.cz E-zdroje
- MeSH
- inbrední kmeny potkanů MeSH
- krysa rodu Rattus MeSH
- kyselina arachidonová MeSH
- kyseliny arachidonové farmakologie MeSH
- medulla oblongata enzymologie MeSH
- mozková kůra enzymologie MeSH
- sodíko-draslíková ATPasa antagonisté a inhibitory MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- kyselina arachidonová MeSH
- kyseliny arachidonové MeSH
- sodíko-draslíková ATPasa MeSH
The effect of arachidonic acid in 5.10(-4) and 5.10(-5) mol.l-1 concentration (as the Na salt, SIGMA) on ouabain-sensitive ATPase (E. C. 3.6.1.3) activity was studied in the cerebral cortex and medulla oblongata of 5-day-old and adult rats. In adult rats, arachidonic acid significantly inhibited ouabain-sensitive ATPase activity in both the cerebral cortex and the medulla oblongata. In 5-day-old rats, only the higher concentration (5.10(-4) mol.l-1) inhibited the enzyme statistically significantly; use of the lower concentration was not followed by any significant changes in Na+-K+-ATPase activity.
