Effect of bilirubin and its photodegradation products on the respiration of mitochondria isolated from rat liver
Physiologia Bohemoslovaca.
1980 ;
29 (4) :
299-303.
Language English Country Czech Republic Media print
Document type Journal Article
Persistent link
https://www.medvik.cz/link/pmid06448415
PubMed
6448415
Knihovny.cz E-resources
- MeSH
- Adenosine Diphosphate pharmacology MeSH
- Bilirubin analogs & derivatives pharmacology MeSH
- Photolysis MeSH
- Mitochondria, Liver metabolism MeSH
- Rats MeSH
- Serum Albumin pharmacology MeSH
- Oxygen Consumption drug effects MeSH
- Succinates metabolism MeSH
- In Vitro Techniques MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Adenosine Diphosphate MeSH
- Bilirubin MeSH
- Serum Albumin MeSH
- Succinates MeSH
In 0.05--0.1 mmol.l-1 concentration, bilirubin inhibits ADP-activated respiration of isolated liver mitochondria; it has no effect on respiration in the absence of ADP. Bilirubin-induced inhibition of respiration is not abolished by serum albumin, but bilirubin bound to serum albumin and the photodegradation products of bilirubin have no inhibitory effect.
