The effect of 1-dodecylpiperidine 1-oxide and N,N'-bis(dodecyldimethyl)-1,2-ethane diammonium dibromide on the spores of Bacillus cereus. particularly their binding to intact spores and spores with reduced cystine bonds, was investigated. The Langmuir type of binding is involved in both cases. Both compounds decreased the thermoresistance of spores. DPNO decreased the fraction of non-germinating spores, the effect of the drug increasing with increasing concentration. This phenomenon was associated with a faster release of dipicolinic acid to the medium. Only microgermination proceeded in the presence of BDED and dipicolinic acid was released only in substantially lower amounts. Both compounds also influenced respiration.

See more in PubMed

Folia Microbiol (Praha). 1978;23(6):493-5 PubMed

J Pharm Pharmacol. 1976 Dec;28(12):941 PubMed

J Bacteriol. 1965 May;89:1340-7 PubMed

Pharm Acta Helv. 1971 Oct-Nov;46(10):671-6 PubMed

J Appl Bacteriol. 1971 Sep;34(3):557-67 PubMed

J Appl Bacteriol. 1970 Mar;33(1):147-56 PubMed

Science. 1958 Jan 3;127(3288):26-7 PubMed

J Bacteriol. 1964 Aug;88:313-8 PubMed

Appl Environ Microbiol. 1977 Jan;33(1):52-8 PubMed

J Bacteriol. 1965 May;89:1180-5 PubMed

Can J Microbiol. 1977 Aug;23(8):935-44 PubMed

Effect of N,N'-bis(alkyldimethyl)-alpha, omega-alkanediammonium dibromides on bacteria of the genus Clostridium

Inhibitory effect of 1-methyldodecyldimethylamine oxide and N,N-bis(dodecyldimethyl)-1,2-ethanediammonium dibromide on the spores of Bacillus cereus