Effect of enhanced bromide intake on the concentration ratio I/Br in the rat thyroid gland
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
7710868
DOI
10.1007/bf02917354
Knihovny.cz E-resources
- MeSH
- Bromides metabolism pharmacology MeSH
- Diet MeSH
- Iodine metabolism MeSH
- Rats MeSH
- Rats, Wistar MeSH
- Iodine Radioisotopes MeSH
- Spectrometry, Gamma MeSH
- Thyroid Gland drug effects metabolism MeSH
- Water Supply analysis MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Bromides MeSH
- Iodine MeSH
- Iodine Radioisotopes MeSH
Interaction of bromine with iodine was studied in the rat thyroid gland under the conditions of different bromide intake. Bromine and iodine in the thyroid dry weight were determined by instrumental neutron activation analysis (INAA). It was found that with increased bromide intake the bromine concentration in the thyroid gland increased with simultaneous decrease in the iodine concentration. The change in the I/Br concentration ratio depends on a number of halogen binding positions and on the bromide supply. The I/Br parameter reacts sensitively to the changes of bromide intake already in the region of low bromine concentration levels.
Biol Trace Elem Res 1995 Jun;48(3):297 PubMed
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Effect of increased bromide intake on iodine excretion in rats
Interaction of bromine with iodine in the rat thyroid gland at enhanced bromide intake
