Histochemical study of aminopeptidase M, aminopeptidase A, and gamma-glutamyltransferase in the nasal cavity of laboratory rodents andman
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
7761786
Knihovny.cz E-resources
- MeSH
- Aminopeptidases analysis MeSH
- CD13 Antigens analysis MeSH
- gamma-Glutamyltransferase analysis MeSH
- Glutamyl Aminopeptidase MeSH
- Histocytochemistry MeSH
- Rats MeSH
- Humans MeSH
- Guinea Pigs MeSH
- Mice MeSH
- Nasal Cavity enzymology MeSH
- Fetus enzymology MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Humans MeSH
- Guinea Pigs MeSH
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Aminopeptidases MeSH
- CD13 Antigens MeSH
- gamma-Glutamyltransferase MeSH
- Glutamyl Aminopeptidase MeSH
The localization of aminopeptidase M (APM), aminopeptidase A (APA) and gama-glutamyltransferase (GGT) activity was studied at light microscope level in the nasal cavity organs of the laboratory rodents (rat, mouse, guinea pig) and human foetuses. All the enzymes were demonstrated histochemically in chloroform-acetone pretreated cryostat sections with application of azocoupling methods (5, 9). These membrane-bound aminopeptidases may participate in the metabolism of peptides in the nasal cavity. They have specific roles as modulators of growth and differentiation of the epithelial cells. The results revealed differences in enzyme patterns between olfactory and respiratory epithelium. GGT seemed to be present only in respiratory epithelium and in the ducts of Bowman's glands. Activity of APM and APA was found mostly in the fibrocytes which adhered to the basal membrane of the epithelium and glands.
