Histochemical study of aminopeptidase M, aminopeptidase A, and gamma-glutamyltransferase in the nasal cavity of laboratory rodents andman
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
7761786
Knihovny.cz E-zdroje
- MeSH
- aminopeptidasy analýza MeSH
- antigeny CD13 analýza MeSH
- gama-glutamyltransferasa analýza MeSH
- glutamylaminopeptidasa MeSH
- histocytochemie MeSH
- krysa rodu Rattus MeSH
- lidé MeSH
- morčata MeSH
- myši MeSH
- nosní dutina enzymologie MeSH
- plod enzymologie MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- lidé MeSH
- morčata MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- aminopeptidasy MeSH
- antigeny CD13 MeSH
- gama-glutamyltransferasa MeSH
- glutamylaminopeptidasa MeSH
The localization of aminopeptidase M (APM), aminopeptidase A (APA) and gama-glutamyltransferase (GGT) activity was studied at light microscope level in the nasal cavity organs of the laboratory rodents (rat, mouse, guinea pig) and human foetuses. All the enzymes were demonstrated histochemically in chloroform-acetone pretreated cryostat sections with application of azocoupling methods (5, 9). These membrane-bound aminopeptidases may participate in the metabolism of peptides in the nasal cavity. They have specific roles as modulators of growth and differentiation of the epithelial cells. The results revealed differences in enzyme patterns between olfactory and respiratory epithelium. GGT seemed to be present only in respiratory epithelium and in the ducts of Bowman's glands. Activity of APM and APA was found mostly in the fibrocytes which adhered to the basal membrane of the epithelium and glands.
