Poskození organizmu monoklonálními imunoglobuliny a moznosti lécby. Cást druhá
[Damage caused by monoclonal immunoglobulins and possibilities of therapy. 2]
Language Czech Country Czech Republic Media print
Document type English Abstract, Journal Article, Review
PubMed
8236864
- MeSH
- Immunoglobulins metabolism MeSH
- Humans MeSH
- Paraproteinemias * immunology metabolism pathology MeSH
- Check Tag
- Humans MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Immunoglobulins MeSH
Monoclonal immunoglobulins (M-Ig) cause due to their chemical structure and physical properties some pathological manifestations. In the text all skin changes are analyzed which are supposed to be associated with M-Ig. Some light chains form amyloid masses which can damage almost all organs. M-Ig can perhaps enhance also the capillary permeability although their role in the capillary leak syndrome remains obscure.