Vplyv prolongovaného hladovania na zmeny aktivity vybraných adaptívnych enzýmov v peceni potkanov
[The effect of prolonged starvation on changes in the activity of selected adaptive enzymes in rat liver]
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
8629317
- MeSH
- Alanine Transaminase metabolism MeSH
- Aspartate Aminotransferases metabolism MeSH
- Starvation blood enzymology MeSH
- Liver enzymology MeSH
- Corticosterone blood MeSH
- Rats MeSH
- Rats, Wistar MeSH
- Tryptophan Oxygenase metabolism MeSH
- Tyrosine Transaminase metabolism MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Names of Substances
- Alanine Transaminase MeSH
- Aspartate Aminotransferases MeSH
- Corticosterone MeSH
- Tryptophan Oxygenase MeSH
- Tyrosine Transaminase MeSH
Male rats of Wistar SPF stain (Velaz Prague) were used to investigate the influence of prolonged starvation on changes in the activity of selected adaptive enzymes in the liver and corticosterone in serum. Analyses were carried out on days 1,2,3,5 and 7 of starvation. The activity of tyrosine aminotransferase significantly increased in the period between days 2 and 5 of starvation, after which a decrease to the level of satiated animals was observed in the terminal period. Activities of tryptophane-2-3-dioxygenase and alanine aminotransferase increased in two phases reaching maximum values on days 2 and 7 of starvation. The activity of aspartate aminotransferase showed a progressive significant increase in dependence on the length of starvation. A more than threefold increase in corticosterone concentration was observed in the serum of starved animals in comparison with satiated rats.
Influence of a single gamma-irradiation on rat microflora
