Distribution of gamma delta T cells in the pig foetus
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
8714772
Knihovny.cz E-zdroje
- MeSH
- monoklonální protilátky MeSH
- orgánová specificita MeSH
- plod cytologie imunologie MeSH
- prasata MeSH
- průtoková cytometrie MeSH
- receptory antigenů T-buněk gama-delta analýza imunologie MeSH
- T-lymfocyty cytologie imunologie MeSH
- těhotenství MeSH
- zvířata MeSH
- Check Tag
- těhotenství MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- monoklonální protilátky MeSH
- receptory antigenů T-buněk gama-delta MeSH
The distribution of gamma delta T cells during different developmental stages of pig foetuses was studied using monoclonal antibodies directed against a ruminant WC1 antigen, a T-cell receptor (TCR) subset epitope, and pig Null T-cell antigen. Binding was revealed by the avidin/biotin/peroxidase technique on cryostat sections and flow cytometry analysis. The extrathymic origin of gamma delta T cells was confirmed: gamma delta T cells appeared in the liver, spleen and peripheral blood sooner than in the thymus. In the course of the second half of gestation, these T cells were found in the dermis and intestinal mucosal compartments which represented the predominant loci of gamma delta T cells after birth.
Prenatal ontogeny of lymphocyte subpopulations in pigs
