Antigenic similarity of central European encephalitis and louping-ill viruses
Language English Country Switzerland Media print
Document type Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
PubMed
8722293
Knihovny.cz E-resources
- MeSH
- Antigens, Viral classification immunology MeSH
- Phylogeny MeSH
- Antibodies, Monoclonal immunology MeSH
- Mice, Inbred BALB C MeSH
- Mice MeSH
- Antibodies, Viral immunology MeSH
- Serotyping MeSH
- Encephalitis Viruses, Tick-Borne classification immunology MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
- Names of Substances
- Antigens, Viral MeSH
- Antibodies, Monoclonal MeSH
- Antibodies, Viral MeSH
Twenty isolates of Central European encephalitis (CEE) virus were compared with 20 isolates of louping-ill (LI) virus in indirect immunofluorescence test (IIFT), using a panel of 17 monoclonal antibodies (MoAbs) prepared against the prototype LI virus. Three Asian members of the tick-borne encephalitis (TBE) complex were also included in the comparison: Turkish sheep encephalitis (TSE), Russian spring-summer encephalitis (RSSE) and Langat (LGT) viruses. Antigenic relationships of the viruses were evaluated by Dice similarity coefficient and cluster analysis. The results revealed antigenic heterogeneity of LI isolates, antigenic homogeneity of CEE isolates, and indicated that CEE and LI are related varieties of Eurasian TBE flavivirus that also includes TSE and RSSE strains.
History of Arbovirus Research in the Czech Republic
