Novel agglutinin in the midgut of the tick Ixodes ricinus
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
8978104
Knihovny.cz E-resources
- MeSH
- Hemagglutinins analysis chemistry MeSH
- Ixodes immunology MeSH
- Hydrogen-Ion Concentration MeSH
- Molecular Weight MeSH
- Polysaccharides MeSH
- Carbohydrates MeSH
- Hemagglutination Inhibition Tests MeSH
- Digestive System immunology MeSH
- Hot Temperature MeSH
- Animals MeSH
- Check Tag
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Hemagglutinins MeSH
- Polysaccharides MeSH
- Carbohydrates MeSH
Haemagglutination activity (HA) was found and characterized in a midgut homogenate of Ixodes ricinus (L.). HA was induced by tick feeding; it was not detected in starved ticks. In a haemagglutination inhibition test, HA showed an affinity for some carbohydrates (N-acetyl-D-galactosamine, N-acetyl-D-glucosamine, rhamnose, and dulcit) and glycoconjugates (especially lipopolysaccharides). Midgut protein components of 37, 60, 65, and 73 kDa were identified by immunoblotting as potential structural subunits of the new agglutinin.
A bite so sweet: the glycobiology interface of tick-host-pathogen interactions
