Monocentrická kontrolovaná klinická studie se Sandimmunem Neoral u nemocných po transplantaci ledviny
[A single-center controlled clinical study with Sandimmune Neoral after kidney transplantation]
Language Czech Country Czech Republic Media print
Document type Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article
PubMed
9650498
- MeSH
- Cyclosporine administration & dosage MeSH
- Immunosuppressive Agents administration & dosage MeSH
- Humans MeSH
- Graft Rejection MeSH
- Kidney Transplantation * MeSH
- Check Tag
- Humans MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Controlled Clinical Trial MeSH
- Clinical Trial MeSH
- Names of Substances
- Cyclosporine MeSH
- Immunosuppressive Agents MeSH
The authors compared in a controlled clinical study two groups of patients after a first renal transplantation treated by triple drug immunosuppressive therapy. In a group of 31 patients the triple combination comprised Sandimmune Neoral. In the control group there were 30 patients who received Sandimmune. No differences were found between the two groups as regards the effectiveness of this treatment and the authors did not confirm a lower incidence of rejections described in patients treated with Sandimmune Neoral. They confirmed, however, a lower interindividual variability of Cy-A levels assessed specifically in patients treated with Sandimmune Neoral.
