Enteral administration of lipid emulsions protects liver cytochrome c oxidase from hepatotoxic action of thioacetamide
Physiological research.
1998 ;
47 (2) :
151-4.
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
Persistent link
https://www.medvik.cz/link/pmid09707000
PubMed
9707000
Knihovny.cz E-resources
- MeSH
- Alanine Transaminase blood MeSH
- Aspartate Aminotransferases blood MeSH
- Emulsions pharmacology MeSH
- Enzyme Inhibitors pharmacology MeSH
- Mitochondria, Liver drug effects enzymology MeSH
- Liver drug effects enzymology MeSH
- Rats MeSH
- Lipids pharmacology MeSH
- Rats, Wistar MeSH
- Electron Transport Complex IV metabolism MeSH
- Thioacetamide toxicity MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Alanine Transaminase MeSH
- Aspartate Aminotransferases MeSH
- Emulsions MeSH
- Enzyme Inhibitors MeSH
- Lipids MeSH
- Electron Transport Complex IV MeSH
- Thioacetamide MeSH
During 48 hours after application sublethal doses of hepatotoxic agent thiacetamide decrease cytochrome c oxidase activity of rat liver homogenate and isolated mitochondria to 46% and 32% of original values, respectively. This decrease may be prevented by simultaneous application of lipid emulsion (mixture of Lipofundin and Mygliol) twice b day.
International journal of experimental pathology.
2011 Aug ;
92 (4) :
281-9.
[epub] 20110317
