Distribution of nitric oxide in cardiovascular system
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
9728489
Knihovny.cz E-zdroje
- MeSH
- calcimycin farmakologie MeSH
- donory oxidu dusnatého farmakologie MeSH
- ionofory farmakologie MeSH
- kardiovaskulární systém metabolismus MeSH
- králíci MeSH
- oxid dusnatý metabolismus MeSH
- techniky in vitro MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- calcimycin MeSH
- donory oxidu dusnatého MeSH
- ionofory MeSH
- oxid dusnatý MeSH
We report here the in vitro measurements of nitric oxide in the cardiovascular system using a porphyrinic sensor specific for NO. Nitric oxide concentrations were measured directly in different parts of the heart and also in different arteries and veins, ranging from 100 microm to 5 mm in diameter. Highest NO. concentrations were found in the heart and particularly in the areas of aortic and pulmonary valves. The NO. concentration in the arteries was higher than in the veins. A clearcut positive correlation was obtained by plotting the vessel diameter and production of nitric oxide.
