The effect of triiodothyronine on cell oxidative capacity in regenerating rat liver
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
9728513
Knihovny.cz E-resources
- MeSH
- DNA metabolism MeSH
- Energy Metabolism MeSH
- Hepatectomy MeSH
- Liver cytology drug effects metabolism MeSH
- Rats MeSH
- Oxidation-Reduction MeSH
- Rats, Wistar MeSH
- Liver Regeneration * MeSH
- Electron Transport Complex IV metabolism MeSH
- Triiodothyronine pharmacology MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- DNA MeSH
- Electron Transport Complex IV MeSH
- Triiodothyronine MeSH
The recovery of total DNA content and recovery of total cytochrome c oxidase activity in the rat liver after partial hepatectomy is accelerated by triiodothyronine applied in three doses, two before and one immediately after liver resection. Triiodothyronine-treated animals already have higher cytochrome c oxidase activity before resection. The recovery of the tissue oxidative capacity after partial hepatectomy is more rapid in triiodothyronine-treated animals. These data indicate that hormonal activation of the liver regeneration process is involved.
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