Odorant concentration and receptor potential in olfactory sensory neurons
Language English Country Ireland Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
9886640
DOI
10.1016/s0303-2647(98)00058-6
PII: S0303-2647(98)00058-6
Knihovny.cz E-resources
- MeSH
- Olfactory Receptor Neurons physiology MeSH
- Models, Neurological MeSH
- Odorants * MeSH
- Receptors, Odorant physiology MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Receptors, Odorant MeSH
The first step of olfactory transduction consists of the interaction of odorant molecules with receptor proteins. This interaction can be described either as a single-step reaction (binding only) or as a double-step one (binding and activation). The number of bound or activated receptors is analyzed as a function of the external concentration of odorant molecules in two models of the neuron environment. In one model the odorant molecules can freely access and leave the vicinity of receptors, whereas in the other a real perireceptor space, partly isolated from the external environment is considered. The steady state and time variable responses to the stimulus are investigated.
References provided by Crossref.org
