Influencing of spatial memory in rats by DSP-4 and mescaline
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
10596419
Knihovny.cz E-resources
- MeSH
- Benzylamines pharmacology MeSH
- Maze Learning drug effects MeSH
- Hallucinogens pharmacology MeSH
- Rats MeSH
- Mescaline pharmacology MeSH
- Neurotoxins pharmacology MeSH
- Memory drug effects MeSH
- Rats, Wistar MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Benzylamines MeSH
- DSP 4 MeSH Browser
- Hallucinogens MeSH
- Mescaline MeSH
- Neurotoxins MeSH
Behavioural effects of two experimental neurotoxins, mescaline and DSP-4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine), on retention of spatial orientation were studied in the T-maze. The stereotaxic administration of both neurotoxins into the selected brain structures was chosen to reveal this effect. The intensity and time course of the neurotoxic effect were dependent on the brain area administered. Nevertheless, the lengthening of the latencies in reaching the goal was generally more marked after mescaline in comparison with DSP-4.
The effect of psilocin on memory acquisition, retrieval, and consolidation in the rat