Remarkable variability of apple mosaic virus capsid protein gene after nucleotide position 141
Language English Country Austria Media print
Document type Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Genetic Variation MeSH
- Humulus virology MeSH
- Ilarvirus chemistry genetics MeSH
- Mutagenesis, Insertional MeSH
- Capsid chemistry genetics MeSH
- Nucleic Acid Conformation MeSH
- Malus virology MeSH
- Molecular Sequence Data MeSH
- RNA, Viral chemistry MeSH
- Protein Structure, Secondary MeSH
- Amino Acid Sequence MeSH
- Base Sequence MeSH
- Sequence Alignment MeSH
- Prunus virology MeSH
- Genes, Viral * MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
- Geographicals
- Europe MeSH
- Names of Substances
- RNA, Viral MeSH
Eight new sequences of European isolates from almond, apple, hop, prune and pear of the Apple mosaic ilarvirus (ApMV) capsid protein gene are presented. A consensus sequence was established as having 654 nucleotides (nt) and two American and two European isolates were identified to have insertions 6 to 15 nucleotides after nt position 141. The insertion resulted in the American isolate A inframeshift repaired with two point insertions 17 and 68 nt downstream. The RNA around the insertion point can potentially form a stable secondary structure with three hairpins. The insertions could stabilise this structure or could be neutral. The predicted folding of the translated protein is not influenced by the insertions or frameshift, and we speculate that the region after nt position 141 is without reasonable selection pressure and represents a hot spot for the accumulation of insertion mutations in ApMV.
References provided by Crossref.org
Reflects the coat protein variability of apple mosaic virus host preference?
GENBANK
AY054385, AY054386, AY054387, AY054388, AY054389
