Remarkable variability of apple mosaic virus capsid protein gene after nucleotide position 141
Jazyk angličtina Země Rakousko Médium print
Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem
- MeSH
- genetická variace MeSH
- Humulus virologie MeSH
- Ilarvirus chemie genetika MeSH
- inzerční mutageneze MeSH
- kapsida chemie genetika MeSH
- konformace nukleové kyseliny MeSH
- Malus virologie MeSH
- molekulární sekvence - údaje MeSH
- RNA virová chemie MeSH
- sekundární struktura proteinů MeSH
- sekvence aminokyselin MeSH
- sekvence nukleotidů MeSH
- sekvenční seřazení MeSH
- slivoň virologie MeSH
- virové geny * MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Evropa MeSH
- Názvy látek
- RNA virová MeSH
Eight new sequences of European isolates from almond, apple, hop, prune and pear of the Apple mosaic ilarvirus (ApMV) capsid protein gene are presented. A consensus sequence was established as having 654 nucleotides (nt) and two American and two European isolates were identified to have insertions 6 to 15 nucleotides after nt position 141. The insertion resulted in the American isolate A inframeshift repaired with two point insertions 17 and 68 nt downstream. The RNA around the insertion point can potentially form a stable secondary structure with three hairpins. The insertions could stabilise this structure or could be neutral. The predicted folding of the translated protein is not influenced by the insertions or frameshift, and we speculate that the region after nt position 141 is without reasonable selection pressure and represents a hot spot for the accumulation of insertion mutations in ApMV.
Citace poskytuje Crossref.org
Reflects the coat protein variability of apple mosaic virus host preference?
GENBANK
AY054385, AY054386, AY054387, AY054388, AY054389
