Isosteric phosphonate pyrrolidine-based dinucleoside monophosphate analogues
Nucleosides, nucleotides & nucleic acids.
2003 May-Aug ;
22 (5-8) :
1065-7.
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
Persistent link
https://www.medvik.cz/link/pmid14565345
PubMed
14565345
DOI
10.1081/ncn-120022737
Knihovny.cz E-resources
- MeSH
- Adenosine chemistry MeSH
- Dinucleoside Phosphates chemistry MeSH
- Hydroxyproline MeSH
- Indicators and Reagents MeSH
- Nucleotides chemical synthesis chemistry MeSH
- Oligonucleotides chemical synthesis MeSH
- Organophosphonates chemistry MeSH
- Poly U chemistry MeSH
- Pyrrolidines chemistry MeSH
- Stereoisomerism MeSH
- Binding Sites MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Adenosine MeSH
- Dinucleoside Phosphates MeSH
- Hydroxyproline MeSH
- Indicators and Reagents MeSH
- Nucleotides MeSH
- Oligonucleotides MeSH
- Organophosphonates MeSH
- Poly U MeSH
- Pyrrolidines MeSH
A novel alpha- and beta-configured pyrrolidine nucleoside phosphonates in adenine series were synthesized from trans-4-hydroxy-L-proline as starting material. d(ApA) analogues were also prepared and studied with respect to their hybridization properties with polyU.
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