Postulation of and evidence for provirus existence in RSV-transformed cells and for an oncogenic activity associated with only part of the RSV genome

. 2003 Oct 23 ; 317 (1-2) : 209-13.

Jazyk angličtina Země Nizozemsko Médium print

Typ dokumentu historické články, časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid14604810

This article gives a historical insight into the establishment of suitable models allowing the postulation that chicken Rous sarcoma virus (RSV) becomes integrated in different cells as a provirus. This is documented by the correspondence between two laboratories involved in these investigations. Special attention is paid to RSV-transformed mammalian cells, their virogenic nature, virus rescue by cell fusion, and finally their use for the oncogene v-src characterization. Two sets of experiments are mentioned, which provided an early indication of a transforming gene present in RSV.

Citace poskytuje Crossref.org

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On board a raft or boat in the retrovirus sea

. 2016 Apr 12 ; 113 (15) : 3927-31. [epub] 20160330

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