Effect of magnesium, calcium and EDTA on slime production by 15 slime-positive and 13 slime-negative Staphylococcus epidermidis strains isolated from various clinical specimens was determined. The slime production on tryptic soy broth was significantly enhanced after addition of 128 mumol/L Mg2+. Similarly, the addition of Ca2+ caused a significant increase in slime production of all tested strains when concentration of Ca2+ exceeded 64 mumol/L. In contrast, in the presence of EDTA the slime production by all strains was significantly reduced. Hence Ca2+ and Mg2+ increase slime production of S. epidermidis. This finding is important in the context of the pathogenesis of biomedical implant infections caused by S. epidermidis.

Department of Microbiology Faculty of Medicine University of Dicle Diyarbakir Turkey

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Dev Med Child Neurol Suppl. 1972;27:25-8 PubMed

Biochem J. 1975 Sep;149(3):519-24 PubMed

Lancet. 1984 Feb 18;1(8373):365-7 PubMed

J Med Microbiol. 1980 May;13(2):351-4 PubMed

Appl Environ Microbiol. 1991 Mar;57(3):863-6 PubMed

Infect Immun. 1982 Jul;37(1):318-26 PubMed

J Clin Microbiol. 1990 Nov;28(11):2578-9 PubMed

Indian J Med Res. 2000 Jan;111:6-10 PubMed

Microbiol Immunol. 1992;36(10):1019-27 PubMed

Eur J Clin Microbiol Infect Dis. 1988 Feb;7(1):30-3 PubMed

Infect Immun. 1991 Jan;59(1):445-8 PubMed

Infect Immun. 1993 Oct;61(10):4473-9 PubMed

Folia Microbiol (Praha). 2002;47(4):458-60 PubMed

Folia Microbiol (Praha). 2000;45(6):485-90 PubMed

J Clin Pathol. 1989 Aug;42(8):872-4 PubMed

J Hosp Infect. 1999 Dec;43 Suppl:S113-25 PubMed

Infect Immun. 1991 Nov;59(11):4187-92 PubMed

J Antimicrob Chemother. 1988 Apr;21 Suppl C:139-48 PubMed

J Clin Microbiol. 1990 Nov;28(11):2442-7 PubMed