Výbĕr vyluhovadla a vypracování technologie výroby extraktu s uklidnujícím úcinkem
[Selection of an extraction agent and development of the technology for producing an extract with sedative effects]
Language Czech Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
15065395
- MeSH
- Chemistry, Pharmaceutical methods MeSH
- Hypnotics and Sedatives isolation & purification MeSH
- Plants, Medicinal chemistry MeSH
- Plant Extracts isolation & purification MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Names of Substances
- Hypnotics and Sedatives MeSH
- Plant Extracts MeSH
The drugs Valerinae radix, Crataegi fructus, Leonuri herba and Melissae folium were used to produce a liquid plant extract. The experiment revealed that the extraction with 70% ethanol achieved the highest concentration of extractable active principles. The optimal conditions for obtaining a sedative extract are established when the method of repercolation is used, and in the production itself the batch of the drug is divided into equally large doses and a pre-prepared mixture of plant drugs is extracted. The extract prepared by this manner remains stable for the whole period of storage, i.e., 24 months.
