The 2001 serological survey in the Czech Republic--diphtheria
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
15080252
Knihovny.cz E-resources
- MeSH
- Corynebacterium diphtheriae immunology MeSH
- Diphtheria Antitoxin administration & dosage immunology MeSH
- Diphtheria blood epidemiology immunology MeSH
- Child MeSH
- Adult MeSH
- Cohort Studies MeSH
- Infant MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Child, Preschool MeSH
- Antibodies, Bacterial blood MeSH
- Data Collection MeSH
- Serologic Tests MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Infant MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Child, Preschool MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Czech Republic epidemiology MeSH
- Names of Substances
- Diphtheria Antitoxin MeSH
- Antibodies, Bacterial MeSH
Diphtheria morbidity in the Czech part of former Czechoslovakia showed a continuous downward trend between 1946 and 1974. Afterwards, sporadic cases of diphtheria were reported in some years. Compulsory vaccination against diphtheria was started in 1946 with a monovaccine, later replaced by bivaccine DiTe. Since 1958, newborns have been vaccinated with DiTePe vaccine. As many as 98% to 100% of the population of age groups under 50 years likely to have been vaccinated have antibody levels > 0.01 lU/ml. About 83% to 88% of the older age groups who represent a naturally immunized population have antibodies as well. This immune status excludes the possibility that diphtheria could spread massively if accidentally imported into the Czech Republic.
